CD300A and SEC22A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD300A	SEC22A
Description		CD300a molecule	SEC22 homolog A, vesicle trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity	SNAP Receptor Activity Protein Binding
	Biological Process	Immune System Process Cell Adhesion Signal Transduction Negative Regulation Of B Cell Proliferation Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Mast Cell Degranulation Negative Regulation Of MAP Kinase Activity Regulation Of Innate Immune Response Negative Regulation Of Fibroblast Proliferation Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Eosinophil Migration	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Membrane Fusion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation	COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Neurological blood protein biomarker levels ( 31320639)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		6 interacting genes: KRT38 KRTAP10-3 SEC22A TMEM218 TMEM60 VMA12	108 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDAF1 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB1 PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC10A1 SLC14A2 SLC18A1 SLC30A2 SLC35H1 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27
Entrez ID		11314	26984
HPRD ID		09492	15313
Ensembl ID		ENSG00000167851	ENSG00000121542
Uniprot IDs		J3QKQ4 Q9UGN4	Q96IW7
PDB IDs		2Q87
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Microvillus Organization Negative Regulation Of Sodium Ion Transport Gamma-aminobutyric Acid Transport Endomembrane System Golgi Localization Maintenance Of Epithelial Cell Apical/basal Polarity Bile Acid Secretion Maintenance Of Cell Polarity Type 2 Metabotropic Glutamate Receptor Binding Glutathione Transport Plasma Membrane Protein Complex Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Microvillus Assembly Type 3 Metabotropic Glutamate Receptor Binding Regulation Of Renal Phosphate Excretion Establishment Of Golgi Localization Negative Regulation Of Fibroblast Migration Channel Activator Activity Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Gamma-aminobutyric Acid Transmembrane Transporter Activity Dopamine Receptor Binding Beta-2 Adrenergic Receptor Binding Phospholipase C-activating Dopamine Receptor Signaling Pathway Renal Phosphate Ion Absorption Chloride Channel Regulator Activity Intracellular Phosphate Ion Homeostasis Gamma-aminobutyric Acid Import Stereocilium Tip Growth Factor Receptor Binding Cerebrospinal Fluid Circulation Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process Proton-transporting V-type ATPase Complex Assembly Oxysterol Binding Vacuolar Proton-transporting V-type ATPase Complex Cellular Response To Increased Oxygen Levels Oligopeptide Transport Establishment Of Epithelial Cell Apical/basal Polarity Auditory Receptor Cell Stereocilium Organization COPI-coated Vesicle Membrane Protein Catabolic Process In The Vacuole Morphogenesis Of An Epithelium	Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Lysosomal Membrane PH-gated Chloride Channel Activity Transmembrane Transport Pattern Recognition Receptor Activity Ascorbate Homeostasis Icosanoid Biosynthetic Process Endoplasmic Reticulum-autophagosome Adaptor Activity Transmembrane Monodehydroascorbate Reductase Activity D-mannose Binding
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