PHYHIP and METTL18

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHYHIP	METTL18
Description		phytanoyl-CoA 2-hydroxylase interacting protein	methyltransferase 18, RPL3 N3(tau)-histidine
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleolus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding	Protein Binding Methyltransferase Activity Transferase Activity Protein-L-histidine N-tele-methyltransferase Activity Heat Shock Protein Binding
	Biological Process	Intracellular Protein Localization	Cytoplasmic Translation Regulation Of Translation Regulation Of Translational Elongation Peptidyl-lysine Monomethylation Methylation Regulation Of Ribosome Biogenesis Regulation Of RRNA Processing
Pathways
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)
Interacting Genes		24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1	4 interacting genes: B3GALT4 PHYHIP RGS2 YAE1
Entrez ID		9796	92342
HPRD ID		16345	14713
Ensembl ID		ENSG00000168490	ENSG00000171806
Uniprot IDs		Q92561	O95568
PDB IDs			4RFQ
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Glycine Import Across Plasma Membrane Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Ganglioside Galactosyltransferase Activity Adenylate Cyclase Inhibitor Activity Negative Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Striated Muscle Contraction Relaxation Of Cardiac Muscle Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Relaxation Of Smooth Muscle Relaxation Of Vascular Associated Smooth Muscle Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Smooth Muscle Contraction N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Ganglioside Biosynthetic Process Relaxation Of Muscle Negative Regulation Of Muscle Contraction Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Tissue Growth Hexosyltransferase Activity Ganglioside Metabolic Process Oligosaccharide Biosynthetic Process Brown Fat Cell Differentiation G-protein Alpha-subunit Binding Response To Amphetamine Glycosphingolipid Biosynthetic Process Maternal Process Involved In Female Pregnancy Negative Regulation Of Muscle Hypertrophy Negative Regulation Of JNK Cascade Negative Regulation Of Organ Growth Positive Regulation Of Heart Contraction Beta-tubulin Binding Negative Regulation Of Cardiac Muscle Hypertrophy Protein Tyrosine Kinase Binding Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Amine
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