PHYHIP and METTL18

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHYHIP	METTL18
Gene Name		phytanoyl-CoA 2-hydroxylase interacting protein	methyltransferase like 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm
	Molecular Function		Protein Methyltransferase Activity
	Biological Process		Protein Methylation
Pathways
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		24 interactors: BAI1 C14orf1 COPS6 DYRK1A EEF1A1 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1	4 interactors: B3GALT4 PHYHIP RGS2 YAE1D1
Entrez ID		9796	92342
HPRD ID		16345	14713
Ensembl ID		ENSG00000168490	ENSG00000171806
Uniprot IDs		Q92561	O95568
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleosome Disassembly Chromatin Organization Mast Cell Activation MRNA Processing RNA Metabolic Process Cellular Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome Interleukin-1 Alpha Secretion RNA Splicing, Via Transesterification Reactions Gene Expression RNA Processing Chromosome Organization Chromatin Modification Positive Regulation Of Viral Process Nucleobase-containing Compound Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Methyl-branched Fatty Acid Metabolic Process Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Glial Cell Development Peripheral Nervous System Development Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Acylglycerol Acyl-chain Remodeling Thyroid Hormone Transport Isoprenoid Metabolic Process Fatty Acid Alpha-oxidation Interleukin-1 Secretion Positive Regulation Of Spindle Checkpoint Regulation Of RNA Metabolic Process	Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Relaxation Of Cardiac Muscle Positive Regulation Of Microtubule Polymerization Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Brown Fat Cell Differentiation Regulation Of Smooth Muscle Contraction Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Polymerization Fat Cell Differentiation Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Regulation Of Muscle Contraction Negative Regulation Of MAPK Cascade Regulation Of Heart Contraction Regulation Of Microtubule-based Process Positive Regulation Of Protein Complex Assembly Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
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