PHYHIP and S100A13

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHYHIP	S100A13
Description		phytanoyl-CoA 2-hydroxylase interacting protein	S100 calcium binding protein A13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Intracellular Protein Localization	Positive Regulation Of Cytokine Production Protein Transport Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Canonical NF-kappaB Signal Transduction Mast Cell Degranulation
Pathways
Drugs			Olopatadine Amlexanox Calcium chloride Calcium Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Plateletcrit ( 32888494)
Interacting Genes		24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1	10 interacting genes: FBXO7 FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 S100A14 SYT1 TNF
Entrez ID		9796	6284
HPRD ID		16345	03586
Ensembl ID		ENSG00000168490	ENSG00000189171
Uniprot IDs		Q92561	Q99584
PDB IDs			1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9
Enriched GO Terms of Interacting Partners?			Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Steroid Biosynthetic Process Regulation Of MAPK Cascade Branch Elongation Involved In Ureteric Bud Branching Cellular Response To Heat Positive Regulation Of Steroid Metabolic Process Immune System Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Mitotic Nuclear Division Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of MAP Kinase Activity Response To Lipopolysaccharide Regulation Of Vasculature Development Regulation Of Angiogenesis Regulation Of Anatomical Structure Morphogenesis Regulation Of Steroid Biosynthetic Process Response To Heat Regulation Of Morphogenesis Of An Epithelium Regulation Of Animal Organ Morphogenesis Response To Molecule Of Bacterial Origin Calcium-dependent Protein Binding Syntaxin-3 Binding Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport Chronic Inflammatory Response To Antigenic Stimulus Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Positive Regulation Of Vitamin D Biosynthetic Process Positive Regulation Of Cell Division Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Regulation Of Steroid Metabolic Process Fever Generation
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