STX1B and STXBP1

Number of citations of the paper that reports this interaction (PMID 12093152)
3

Data Source:
BioGRID (pull down)

		STX1B	STXBP1
Gene Name		syntaxin 1B	syntaxin binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane SNARE Complex	Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Platelet Alpha Granule Protein Complex Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Kinase Binding Protein Domain Specific Binding	SNARE Binding Syntaxin-1 Binding Protein Kinase Binding Protein Domain Specific Binding Syntaxin Binding Identical Protein Binding Poly(A) RNA Binding Protein N-terminus Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Pathogenesis Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Positive Regulation Of Excitatory Postsynaptic Membrane Potential	Platelet Degranulation Energy Reserve Metabolic Process Vesicle Docking Involved In Exocytosis Synaptic Transmission Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axon Target Recognition Regulation Of Synaptic Vesicle Priming Glutamate Secretion Protein Transport Synaptic Vesicle Maturation Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Synaptic Transmission, GABAergic Regulation Of SNARE Complex Assembly Negative Regulation Of Neuron Apoptotic Process Small Molecule Metabolic Process Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion Protein Stabilization Long Term Synaptic Depression Platelet Aggregation Protein Localization To Plasma Membrane
Pathways		Uptake and actions of bacterial toxins Toxicity of botulinum toxin type C (BoNT/C) Neurotoxicity of clostridium toxins	Integration of energy metabolism Regulation of insulin secretion
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: SNAP23 STXBP1 UNC13B VAMP1 VAMP2	27 interactors: APBA1 APBA2 APP CDK5 CDK5R1 DOC2A DOC2B DYT10 HGS MAPT NEFH NEFM PLD1 PLD2 PRKCA PRKCB PRKCG SQSTM1 STX11 STX19 STX1A STX1B STX2 STX3 SYTL4 TRIM38 USO1
Entrez ID		112755	6812
HPRD ID		18126	04235
Ensembl ID		ENSG00000099365	ENSG00000136854
Uniprot IDs		P61266	B7Z1V5 P61764 Q68CM6
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Secretion By Cell Regulation Of Neurotransmitter Levels Glutamate Secretion Neurotransmitter Transport Secretion Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle Fusion Synaptic Vesicle Exocytosis Acid Secretion Establishment Of Organelle Localization Organelle Fusion Dicarboxylic Acid Transport Organelle Localization Vesicle-mediated Transport Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Priming Membrane Fusion Synaptic Transmission Regulation Of Exocytosis Amino Acid Transport Anion Transport Regulation Of Synaptic Plasticity Establishment Of Localization In Cell Membrane Organization Cell-cell Signaling Cellular Localization Protein Complex Assembly Regulation Of Synaptic Vesicle Exocytosis Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Regulation Of Synaptic Vesicle Transport Cellular Protein Complex Assembly Leukocyte Degranulation Regulation Of Vesicle-mediated Transport Regulated Secretory Pathway Organic Anion Transport Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Regulation Of Neurotransmitter Secretion Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Ion Transport Cellular Macromolecular Complex Assembly	Synaptic Transmission Synaptic Vesicle Exocytosis Synaptic Vesicle Fusion To Presynaptic Membrane Neurotransmitter Secretion Synaptic Vesicle Transport Cell-cell Signaling Regulation Of Neurotransmitter Levels Establishment Of Localization In Cell Secretion By Cell Neurotransmitter Transport Vesicle Fusion Establishment Of Vesicle Localization Vesicle Localization Secretion Establishment Of Organelle Localization Cellular Localization Exocytosis Organelle Fusion Vesicle Docking Intracellular Transport Membrane Docking Organelle Localization Membrane Fusion Protein Localization Regulation Of Exocytosis Regulation Of Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Protein Transport Signaling Transport Cell Communication Vesicle Organization Positive Regulation Of Exocytosis Vesicle-mediated Transport Cellular Protein Localization Regulation Of Vesicle-mediated Transport Peptidyl-threonine Phosphorylation Regulation Of Secretion Axon Cargo Transport Regulation Of Signaling Organelle Organization Positive Regulation Of Secretion Histone H3-T6 Phosphorylation Neurofilament Bundle Assembly Positive Regulation Of Transport Serine Phosphorylation Of STAT3 Protein Nervous System Development Regulation Of Synaptic Vesicle Transport
Tagcloud ?			16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss kcnq2 magi2 mef2c microdeletions microduplications scn2a spasms xq28
Tagcloud (Difference) ?			16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss kcnq2 magi2 mef2c microdeletions microduplications scn2a spasms xq28
Tagcloud (Intersection) ?