STX1B and TXLNA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX1B	TXLNA
Description		syntaxin 1B	taxilin alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Lamina Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Endomembrane System Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane Presynapse	Extracellular Region Cytoplasm Cytosol Membrane
	Molecular Function	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding	Protein Binding Syntaxin Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Exocytosis B Cell Activation
Pathways		Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions	Other interleukin signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325) Walking pace ( 33128006)
Interacting Genes		30 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB SNAP23 SNAP29 SNAP47 SNCA STX2 STX4 STXBP1 TMEM167B TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5	95 interacting genes: AXIN2 AZI2 BIN3 BRCA1 BRMS1L BTF3 BTF3L4 CBY2 CCDC112 CCDC136 CCDC146 CCDC196 CCDC33 CCDC57 CCHCR1 CDC5L CDR2 CEBPA CEP44 CEP57 CEP57L1 CEP63 CFAP53 DEUP1 DMAP1 DRC4 DTNB EIF4ENIF1 EPN2 FAM81A FAM9A GOLGA2 GOLGA6A GORASP2 HAUS3 HYPK IKBKG KANK2 KIAA1328 KRT13 KRT15 KRT20 KRT24 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRT75 LCA5 LZTS1 MBIP MCC MEOX1 MEOX2 MIS18A NACA NDC80 NKAPD1 NMI NSMCE2 NUP62 OLIG2 PIAS2 PPFIA1 PPP1R13B PRDM16 PRPF3 RASSF8 RCOR3 RINT1 SIKE1 SLC25A21-AS1 SMARCE1 SNCA SNF8 SORBS3 SREK1 STMN2 STX1A STX1B STX3 STX4 TBC1D1 TCL1A TFIP11 TNIP1 TP53BP2 TTC33 TXLNB USHBP1 UTP14C WASHC1 WASHC3
Entrez ID		112755	200081
HPRD ID		18126	09408
Ensembl ID		ENSG00000099365	ENSG00000084652
Uniprot IDs		P61266	P40222
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Syntaxin Binding Exocytosis Synaptic Vesicle Priming Vesicle-mediated Transport Vesicle Fusion Organelle Membrane Fusion SNARE Complex Assembly Secretion Secretion By Cell Organelle Fusion Membrane Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Vesicle Organization Membrane Organization Synaptic Vesicle Membrane Organization SNARE Binding Organelle Localization By Membrane Tethering Membrane Docking Regulation Of Synaptic Vesicle Priming Establishment Of Localization In Cell Membrane Protein-containing Complex Organization Syntaxin-1 Binding Vesicle Docking Positive Regulation Of Protein Transport Protein-containing Complex Assembly Positive Regulation Of Protein Localization Positive Regulation Of Secretion By Cell Positive Regulation Of Exocytosis Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Exocytosis Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Transport Vesicle Cellular Component Assembly Regulated Exocytosis Cornified Envelope Assembly Neuronal Dense Core Vesicle Exocytosis Cellular Localization Presynapse Regulation Of Secretion By Cell Establishment Of Protein Localization Dense Core Granule Exocytosis Positive Regulation Of Transport Synaptic Vesicle Membrane	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Structural Molecule Activity Microtubule Organizing Center Organization Protein Binding Cytoskeleton Organization Centriole Assembly Centriole Centrosome Cycle Centriole Replication Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytoplasm Membraneless Organelle Assembly Negative Regulation Of Protein Localization To Endoplasmic Reticulum SNARE Binding Microtubule-based Process HMG Box Domain Binding SNARE Complex Assembly Organelle Assembly SNAP Receptor Activity Nascent Polypeptide-associated Complex Tissue Morphogenesis SNARE Complex Exocytosis Cell Differentiation Negative Regulation Of Cell Cycle Cytosol Positive Regulation Of Neurotransmitter Secretion Identical Protein Binding Neurotransmitter Transport Regulation Of Cell Cycle Spindle Pole Centrosome Somite Specification De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Cellular Developmental Process Vesicle Docking De Novo Centriole Assembly Microtubule Binding Establishment Of Protein Localization Manchette Assembly Regulation Of Cytoskeleton Organization
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