STX1B and SNAP29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX1B	SNAP29
Description		syntaxin 1B	synaptosome associated protein 29
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Lamina Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Endomembrane System Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane Presynapse	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cilium Membrane Ciliary Pocket Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Cell Projection Ciliary Membrane Presynapse
	Molecular Function	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Exocytosis Vesicle Targeting Autophagy Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Cell Projection Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cilium Assembly Membrane Fusion Autophagosome Maturation
Pathways		Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions	Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases			Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS		Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325) Walking pace ( 33128006)
Interacting Genes		30 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB SNAP23 SNAP29 SNAP47 SNCA STX2 STX4 STXBP1 TMEM167B TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5	24 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX17 STX1A STX1B STX2 STX3 STX6 STX7 TXNRD3 VAMP1 VAMP7
Entrez ID		112755	9342
HPRD ID		18126	11968
Ensembl ID		ENSG00000099365	ENSG00000099940
Uniprot IDs		P61266	O95721
PDB IDs			4WY4 7BV6
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Syntaxin Binding Exocytosis Synaptic Vesicle Priming Vesicle-mediated Transport Vesicle Fusion Organelle Membrane Fusion SNARE Complex Assembly Secretion Secretion By Cell Organelle Fusion Membrane Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Vesicle Organization Membrane Organization Synaptic Vesicle Membrane Organization SNARE Binding Organelle Localization By Membrane Tethering Membrane Docking Regulation Of Synaptic Vesicle Priming Establishment Of Localization In Cell Membrane Protein-containing Complex Organization Syntaxin-1 Binding Vesicle Docking Positive Regulation Of Protein Transport Protein-containing Complex Assembly Positive Regulation Of Protein Localization Positive Regulation Of Secretion By Cell Positive Regulation Of Exocytosis Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Exocytosis Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Transport Vesicle Cellular Component Assembly Regulated Exocytosis Cornified Envelope Assembly Neuronal Dense Core Vesicle Exocytosis Cellular Localization Presynapse Regulation Of Secretion By Cell Establishment Of Protein Localization Dense Core Granule Exocytosis Positive Regulation Of Transport Synaptic Vesicle Membrane	SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion SNARE Binding Organelle Fusion Membrane Fusion Vesicle Docking Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Intracellular Protein Transport Endomembrane System Intracellular Transport Establishment Of Localization In Cell Protein Transport Cellular Localization Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Membrane Organization Exocytosis Intracellular Protein Localization Organelle Localization Regulation Of Synaptic Vesicle Priming Syntaxin Binding Secretion By Cell Synaptic Vesicle Organelle Organization Synaptic Vesicle Membrane Endocytic Recycling Secretion Ciliary Pocket Membrane Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Recycling Endosome Membrane Regulated Exocytosis Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Synaptic Vesicle Endocytosis Endosomal Transport Presynaptic Endocytosis Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Plasma Membrane Azurophil Granule Membrane Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
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