DDX20 and STXBP3

Number of citations of the paper that reports this interaction (PubMedID 12065586)
0

Data Source:
HPRD (in vivo)

		DDX20	STXBP3
Description		DEAD-box helicase 20	syntaxin binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Nuclear Body Transcription Repressor Complex SMN Complex Protein-containing Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Cajal Bodies	Cytoplasm Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Secretory Granule Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Histone Deacetylase Binding DNA-binding Transcription Factor Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Oogenesis Regulation Of Steroid Biosynthetic Process	Intracellular Glucose Homeostasis Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Response To Stress Immune Response Brain Development Protein Transport Vesicle-mediated Transport Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Regulated Exocytosis Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of D-glucose Import Negative Regulation Of Transport Regulation Of Biological Quality Platelet Aggregation Cellular Response To Type II Interferon Presynaptic Dense Core Vesicle Exocytosis
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery	Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)	Fat distribution (HIV) ( 21897333)
Interacting Genes		33 interacting genes: AGO2 APP CFTR CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53	15 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNCA SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2
Entrez ID		11218	6814
HPRD ID		05859	10517
Ensembl ID		ENSG00000064703	ENSG00000116266
Uniprot IDs		Q9H4N4 Q9UHI6	O00186
PDB IDs		2OXC 3B7G
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Protein-containing Complex Assembly U2 SnRNP Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex RNA Splicing U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP MRNA Processing U4/U6 X U5 Tri-snRNP Complex MRNA Metabolic Process U2-type Precatalytic Spliceosome Cellular Component Assembly SMN Complex RNA Processing Gemini Of Cajal Bodies Nucleoplasm MRNA Splicing, Via Spliceosome RNA Methylation Precatalytic Spliceosome Catalytic Step 2 Spliceosome RNA Binding Spliceosomal Complex Macromolecule Methylation RNA Metabolic Process RNA Modification Nucleus Nuclear Body Ribonucleoprotein Complex Methylation Protein-containing Complex Spliceosomal Tri-snRNP Complex Transcription Repressor Complex Nucleic Acid Metabolic Process Rhythmic Process Cytosol Histone Deacetylase Complex	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Gemini Of Cajal Bodies Protein-RNA Complex Assembly RNA Splicing Protein-containing Complex Assembly Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex MRNA Processing Protein-containing Complex Organization MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Cellular Component Assembly 7-methylguanosine Cap Hypermethylation U4 SnRNP SNARE Complex Assembly Methylosome RNA Processing Regulation Of Exocytosis Nuclear Body U1 SnRNP U5 SnRNP Cytosol U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome Synaptic Vesicle Exocytosis Histone Pre-mRNA DCP Binding U4/U6 X U5 Tri-snRNP Complex RNA Metabolic Process U2-type Precatalytic Spliceosome PICln-Sm Protein Complex Long-term Synaptic Potentiation Spliceosomal Complex U7 SnRNP Neutrophil Degranulation SNARE Binding MRNA Splicing, Via Spliceosome Exocytosis RNA Methylation Positive Regulation Of Exocytosis Catalytic Step 2 Spliceosome Specific Granule Vesicle-mediated Transport In Synapse Response To Cytokine Regulation Of Vesicle-mediated Transport Response To Peptide
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