STXBP3 and RPL3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		STXBP3	RPL3
Gene Name		syntaxin binding protein 3	ribosomal protein L3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Extracellular Vesicular Exosome Tertiary Granule	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Brain Development Blood Coagulation Protein Transport Glucose Transport Protein To Membrane Docking Insulin Secretion Platelet Activation Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Protein Heterooligomerization Membrane Organization Platelet Aggregation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Cellular Response To Interleukin-4
Pathways		Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		14 interactors: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	4 interactors: NDRG1 NUMB SIK1 STXBP3
Entrez ID		6814	6122
HPRD ID		10517	16042
Ensembl ID		ENSG00000116266	ENSG00000100316
Uniprot IDs		O00186	B3KS36 P39023 Q96QL0
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly MRNA Processing NcRNA Metabolic Process Cellular Component Assembly RNA Processing Gene Expression Spliceosomal Complex Assembly RNA Metabolic Process Histone MRNA Metabolic Process Regulation Of Exocytosis Regulation Of Insulin Secretion Termination Of RNA Polymerase II Transcription Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion Nucleobase-containing Compound Metabolic Process Leukocyte Degranulation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Long-term Synaptic Potentiation Regulation Of Secretion Vesicle Fusion Regulation Of Hormone Secretion Regulated Secretory Pathway Synaptic Vesicle Exocytosis Cell Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis DNA-templated Transcription, Termination Exocytosis Vesicle Docking Organelle Fusion MRNA 3'-end Processing Membrane Docking Nitrogen Compound Metabolic Process Positive Regulation Of Eosinophil Degranulation Histone H3-T6 Phosphorylation Post-Golgi Vesicle-mediated Transport Membrane Organization Regulation Of Vesicle-mediated Transport Regulation Of Protein Secretion RNA 3'-end Processing Eosinophil Degranulation Neurotransmitter Secretion	Negative Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Polarized Epithelial Cell Differentiation Negative Regulation Of CREB Transcription Factor Activity Positive Regulation Of Anoikis Neuroblast Division In Subventricular Zone System Development Positive Regulation Of Spindle Checkpoint Neutrophil Degranulation Protein To Membrane Docking Neutrophil Activation Involved In Immune Response Positive Regulation Of Cell Cycle Checkpoint Multicellular Organismal Development Anatomical Structure Development Negative Regulation Of Gluconeogenesis Forebrain Neuroblast Division Leukocyte Activation Developmental Process Regulation Of Anoikis Regulation Of Triglyceride Biosynthetic Process Peripheral Nervous System Myelin Maintenance Signaling Negative Regulation Of Calcium Ion-dependent Exocytosis Nervous System Development Negative Regulation Of Protein Localization To Plasma Membrane Neutrophil Mediated Immunity Cell Communication Lateral Ventricle Development Neutrophil Activation Entrainment Of Circadian Clock By Photoperiod Regulation Of Spindle Checkpoint Somatic Stem Cell Division Photoperiodism Entrainment Of Circadian Clock Cell Activation Myelin Maintenance Negative Regulation Of Notch Signaling Pathway Mast Cell Activation Regulation Of Triglyceride Metabolic Process Brain Development Regulation Of Cell Cycle Checkpoint Negative Regulation Of Exocytosis Head Development Platelet Aggregation Stem Cell Division Leukocyte Degranulation Insulin Secretion Ventricular System Development Myelination In Peripheral Nervous System Organ Development Membrane Organization
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized	4a act1 apparatus carrying compete differing efficiencies enter entry exponential hsp12 hsp26 idea inert lacz leaders mrnas pgk1 polysome pyk1 raising rp29 saccharomyces starvation stationary thi4 translatabilities translated translational
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized	4a act1 apparatus carrying compete differing efficiencies enter entry exponential hsp12 hsp26 idea inert lacz leaders mrnas pgk1 polysome pyk1 raising rp29 saccharomyces starvation stationary thi4 translatabilities translated translational
Tagcloud (Intersection) ?