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DDX20 and DHX9
Number of citations of the paper that reports this interaction (PMID
11149922
)
46
Data Source:
HPRD
(in vivo, in vitro)
DDX20
DHX9
Gene Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DEAH (Asp-Glu-Ala-His) box helicase 9
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Membrane
Transcriptional Repressor Complex
SMN Complex
SMN-Sm Protein Complex
Gemini Of Coiled Bodies
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
Cytosol
Membrane
Ribonucleoprotein Complex
Cytoplasmic Ribonucleoprotein Granule
CRD-mediated MRNA Stability Complex
Molecular Function
DNA Binding
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Protein Domain Specific Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
RNA Helicase Activity
ATP-dependent DNA Helicase Activity
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Spliceosomal Tri-snRNP Complex Assembly
Spliceosomal SnRNP Assembly
RNA Processing
Gene Expression
NcRNA Metabolic Process
Positive Regulation Of Apoptotic Process
Oogenesis
Regulation Of Steroid Biosynthetic Process
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
RNA Processing
Circadian Rhythm
RNA Splicing
Gene Expression
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Cellular Response To Heat
Innate Immune Response
CRD-mediated MRNA Stabilization
Pathways
snRNP Assembly
Metabolism of non-coding RNA
mRNA Splicing
Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor TLR6:TLR2 Cascade
RIP-mediated NFkB activation via ZBP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
ZBP1(DAI) mediated induction of type I IFNs
MyD88 dependent cascade initiated on endosome
MyD88:Mal cascade initiated on plasma membrane
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Toll Like Receptor 9 (TLR9) Cascade
Innate Immune System
Processing of Capped Intron-Containing Pre-mRNA
TRIF-mediated TLR3/TLR4 signaling
Cytosolic sensors of pathogen-associated DNA
mRNA Splicing - Major Pathway
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
TRAF6 mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
AGO2
APP
CRYAB
DHX9
ETV3
GEMIN2
GEMIN4
GEMIN5
HDAC2
HDAC5
LSM2
NCOR1
NCOR2
NR0B2
PRRC2A
RN7SL1
RNU1-1
RNU2-1
SIN3A
SMN1
SMN2
SNRPB
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SNRPG
SNUPN
STXBP2
STXBP3
40 interactors:
ACTA1
AKAP8L
APBB1
BRCA1
DDX20
DDX5
EIF2AK2
EWSR1
GEMIN2
GEMIN4
GTF2B
H2AFX
HDLBP
HNRNPC
HNRNPK
IL7R
ILF3
JUN
KHDRBS1
MBD2
MGEA5
NXF1
PCNA
POLR2A
PRMT1
PRPF40A
PRPF8
RBM4
RELA
SMN1
SMN2
SNRPB
SNRPB2
SRPK1
SSRP1
STAU1
TBP
TOP2A
UBE2I
YWHAQ
Entrez ID
11218
1660
HPRD ID
05859
04386
Ensembl ID
ENSG00000064703
ENSG00000135829
Uniprot IDs
Q9H4N4
Q9UHI6
B3KU66
Q08211
PDB IDs
2OXC
3B7G
3LLM
3VYX
3VYY
Enriched GO Terms of Interacting Partners
?
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Processing
Ribonucleoprotein Complex Assembly
MRNA Metabolic Process
RNA Processing
RNA Splicing
Ribonucleoprotein Complex Biogenesis
RNA Metabolic Process
Gene Expression
NcRNA Metabolic Process
Cellular Macromolecular Complex Assembly
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Component Assembly
Cellular Nitrogen Compound Metabolic Process
Spliceosomal Complex Assembly
Nitrogen Compound Metabolic Process
Histone MRNA Metabolic Process
MRNA 3'-end Processing
Termination Of RNA Polymerase II Transcription
RNA 3'-end Processing
Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Termination
Cellular Metabolic Process
Transcription, DNA-templated
Notch Signaling Pathway
RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Rhythmic Process
Neutrophil Degranulation
Histone Deacetylation
Protein Deacetylation
Cellular Macromolecule Biosynthetic Process
Neutrophil Activation Involved In Immune Response
Negative Regulation Of Cellular Metabolic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Histone H4 Deacetylation
Gene Silencing
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
MRNA Processing
RNA Splicing
MRNA Metabolic Process
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Spliceosomal SnRNP Assembly
Nitrogen Compound Metabolic Process
Regulation Of Viral Process
Regulation Of Viral Genome Replication
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Viral Process
Positive Regulation Of DNA Metabolic Process
Regulation Of Gene Expression
Ribonucleoprotein Complex Assembly
Viral Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Cellular Macromolecular Complex Assembly
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Chromosome Organization
Positive Regulation Of Response To DNA Damage Stimulus
Negative Regulation Of Viral Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Viral Genome Replication
Tagcloud
?
acting
box
coactivators
concentrate
corepressors
creb
ddx17
ddx5
deacetylases
dexd
dhx9
dissociate
dp103
helicase
helicases
hydrolysis
includes
machinery
members
modulation
multifunctional
p68
p72
require
rna
roles
shall
unwind
unwindases
Tagcloud (Difference)
?
acting
box
coactivators
concentrate
corepressors
creb
ddx17
ddx5
deacetylases
dexd
dhx9
dissociate
dp103
helicase
helicases
hydrolysis
includes
machinery
members
modulation
multifunctional
p68
p72
require
rna
roles
shall
unwind
unwindases
Tagcloud (Intersection)
?