DDX20 and ETV3

Number of citations of the paper that reports this interaction (PMID 12007404)
28

Data Source:
HPRD (in vitro)

		DDX20	ETV3
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	ets variant 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Transcriptional Repressor Complex SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Transcriptional Repressor Complex
	Molecular Function	DNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Molecular_function Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Gene Expression NcRNA Metabolic Process Positive Regulation Of Apoptotic Process Oogenesis Regulation Of Steroid Biosynthetic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Biological_process Cell Differentiation
Pathways		snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions		31 interactors: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 LSM2 NCOR1 NCOR2 NR0B2 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3	3 interactors: APP DDX20 WHSC1L1
Entrez ID		11218	2117
HPRD ID		05859	01282
Ensembl ID		ENSG00000064703	ENSG00000117036
Uniprot IDs		Q9H4N4 Q9UHI6	P41162
PDB IDs		2OXC 3B7G
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing Ribonucleoprotein Complex Assembly MRNA Metabolic Process RNA Processing RNA Splicing Ribonucleoprotein Complex Biogenesis RNA Metabolic Process Gene Expression NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Component Assembly Cellular Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process MRNA 3'-end Processing Termination Of RNA Polymerase II Transcription RNA 3'-end Processing Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Termination Cellular Metabolic Process Transcription, DNA-templated Notch Signaling Pathway RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Neutrophil Degranulation Histone Deacetylation Protein Deacetylation Cellular Macromolecule Biosynthetic Process Neutrophil Activation Involved In Immune Response Negative Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone H4 Deacetylation Gene Silencing Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Metabolic Process Axon Choice Point Recognition MRNA Processing Histone H3-K27 Methylation Neuron Remodeling MRNA Metabolic Process RNA Processing Spliceosomal Tri-snRNP Complex Assembly Cellular Copper Ion Homeostasis RNA Metabolic Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Gene Expression Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Histone H3-K4 Methylation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Spliceosomal SnRNP Assembly Reproduction Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Axon Cargo Transport Negative Regulation Of Nucleic Acid-templated Transcription Mating Neuromuscular Junction Development Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning
Tagcloud ?		acting box coactivators concentrate corepressors creb ddx17 ddx5 deacetylases dexd dhx9 dissociate dp103 helicase helicases hydrolysis includes machinery members modulation multifunctional p68 p72 require rna roles shall unwind unwindases	1q 1q21 1q32 8q24 amplification androgen bac bands carcinogenesis cgh clones copy crisp3 elf3 elk4 ets gain gains genomic impacts irrespective irrespectively loci myc number oncogene repressor respondent worst
Tagcloud (Difference) ?		acting box coactivators concentrate corepressors creb ddx17 ddx5 deacetylases dexd dhx9 dissociate dp103 helicase helicases hydrolysis includes machinery members modulation multifunctional p68 p72 require rna roles shall unwind unwindases	1q 1q21 1q32 8q24 amplification androgen bac bands carcinogenesis cgh clones copy crisp3 elf3 elk4 ets gain gains genomic impacts irrespective irrespectively loci myc number oncogene repressor respondent worst
Tagcloud (Intersection) ?