STXBP3 and SNRPD2

Number of citations of the paper that reports this interaction (PMID 12065586)
31

Data Source:
HPRD (in vivo)

		STXBP3	SNRPD2
Gene Name		syntaxin binding protein 3	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Extracellular Vesicular Exosome Tertiary Granule	Nucleoplasm Spliceosomal Complex U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Brain Development Blood Coagulation Protein Transport Glucose Transport Protein To Membrane Docking Insulin Secretion Platelet Activation Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Protein Heterooligomerization Membrane Organization Platelet Aggregation	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression NcRNA Metabolic Process
Pathways		Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing snRNP Assembly mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		14 interactors: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	25 interactors: CEP70 CLNS1A DDX20 DMTN EEF1G EGFR GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF STRAP STXBP2 STXBP3 WDR77 ZCCHC10
Entrez ID		6814	6633
HPRD ID		10517	03038
Ensembl ID		ENSG00000116266	ENSG00000125743
Uniprot IDs		O00186	P62316
PDB IDs			1B34 1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly MRNA Processing NcRNA Metabolic Process Cellular Component Assembly RNA Processing Gene Expression Spliceosomal Complex Assembly RNA Metabolic Process Histone MRNA Metabolic Process Regulation Of Exocytosis Regulation Of Insulin Secretion Termination Of RNA Polymerase II Transcription Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion Nucleobase-containing Compound Metabolic Process Leukocyte Degranulation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Long-term Synaptic Potentiation Regulation Of Secretion Vesicle Fusion Regulation Of Hormone Secretion Regulated Secretory Pathway Synaptic Vesicle Exocytosis Cell Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis DNA-templated Transcription, Termination Exocytosis Vesicle Docking Organelle Fusion MRNA 3'-end Processing Membrane Docking Nitrogen Compound Metabolic Process Positive Regulation Of Eosinophil Degranulation Histone H3-T6 Phosphorylation Post-Golgi Vesicle-mediated Transport Membrane Organization Regulation Of Vesicle-mediated Transport Regulation Of Protein Secretion RNA 3'-end Processing Eosinophil Degranulation Neurotransmitter Secretion	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly RNA Splicing MRNA Processing Ribonucleoprotein Complex Biogenesis MRNA Metabolic Process RNA Processing NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Cellular Component Assembly Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Cellular Response To Estradiol Stimulus Neutrophil Mediated Immunity Neutrophil Activation Cellular Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Response To Estrogen Stimulus Cellular Process Leukocyte Degranulation Alkanesulfonate Metabolic Process Positive Regulation Of Platelet Aggregation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Protein Secretion By Platelet Calcium-mediated Signaling Using Extracellular Calcium Source Interleukin-7-mediated Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Vesicle Docking Regulation Of Epithelial Cell Proliferation Actin Filament Reorganization Membrane Docking Activation Of Phospholipase A2 Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Calcium-mediated Signaling Cell Activation Exocytosis
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?