STXBP3 and GEMIN5

Number of citations of the paper that reports this interaction (PubMedID 12065586)
0

Data Source:
HPRD (in vivo)

		STXBP3	GEMIN5
Description		syntaxin binding protein 3	gem nuclear organelle associated protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Secretory Granule Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding
	Biological Process	Intracellular Glucose Homeostasis Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Response To Stress Immune Response Brain Development Protein Transport Vesicle-mediated Transport Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Regulated Exocytosis Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of D-glucose Import Negative Regulation Of Transport Regulation Of Biological Quality Platelet Aggregation Cellular Response To Type II Interferon Presynaptic Dense Core Vesicle Exocytosis	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing Translation Regulation Of Translation RNA Splicing Protein-containing Complex Assembly
Pathways		Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane	snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Venous thromboembolism ( 32232851)
Interacting Genes		15 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNCA SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	22 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNF10 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2
Entrez ID		6814	25929
HPRD ID		10517	06109
Ensembl ID		ENSG00000116266	ENSG00000082516
Uniprot IDs		O00186	B7ZLC9 Q58EZ8 Q8TEQ6
PDB IDs			5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS 7XDT 7XGR
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Gemini Of Cajal Bodies Protein-RNA Complex Assembly RNA Splicing Protein-containing Complex Assembly Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex MRNA Processing Protein-containing Complex Organization MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Cellular Component Assembly 7-methylguanosine Cap Hypermethylation U4 SnRNP SNARE Complex Assembly Methylosome RNA Processing Regulation Of Exocytosis Nuclear Body U1 SnRNP U5 SnRNP Cytosol U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome Synaptic Vesicle Exocytosis Histone Pre-mRNA DCP Binding U4/U6 X U5 Tri-snRNP Complex RNA Metabolic Process U2-type Precatalytic Spliceosome PICln-Sm Protein Complex Long-term Synaptic Potentiation Spliceosomal Complex U7 SnRNP Neutrophil Degranulation SNARE Binding MRNA Splicing, Via Spliceosome Exocytosis RNA Methylation Positive Regulation Of Exocytosis Catalytic Step 2 Spliceosome Specific Granule Vesicle-mediated Transport In Synapse Response To Cytokine Regulation Of Vesicle-mediated Transport Response To Peptide	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly 7-methylguanosine Cap Hypermethylation Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Spliceosomal Complex Assembly U2 SnRNP Protein-RNA Complex Assembly U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Methylation Catalytic Step 2 Spliceosome Precatalytic Spliceosome Spliceosomal Complex Protein-containing Complex Assembly Macromolecule Methylation MRNA Metabolic Process Protein-containing Complex Organization SMN Complex Gemini Of Cajal Bodies RNA Modification RNA Processing MRNA Splicing, Via Spliceosome Methylation Spliceosomal Tri-snRNP Complex Cellular Component Assembly Ribonucleoprotein Complex RNA Metabolic Process Telomerase Holoenzyme Complex Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear Body Histone Pre-mRNA DCP Binding RNA Binding Commitment Complex U1 SnRNP Binding JNK Cascade Cytosol
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