STXBP3 and STXBP2

Number of citations of the paper that reports this interaction (PMID 12065586)
31

Data Source:
HPRD (in vivo)

		STXBP3	STXBP2
Gene Name		syntaxin binding protein 3	syntaxin binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Extracellular Vesicular Exosome Tertiary Granule	Cytosol Plasma Membrane SNARE Complex Specific Granule Azurophil Granule Cytolytic Granule Extracellular Vesicular Exosome Tertiary Granule
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding	Protein Binding Syntaxin-3 Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Brain Development Blood Coagulation Protein Transport Glucose Transport Protein To Membrane Docking Insulin Secretion Platelet Activation Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Protein Heterooligomerization Membrane Organization Platelet Aggregation	Leukocyte Mediated Cytotoxicity Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation
Pathways		Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		14 interactors: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	13 interactors: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		6814	6813
HPRD ID		10517	03423
Ensembl ID		ENSG00000116266	ENSG00000076944
Uniprot IDs		O00186	B4E175 E7EQD5 Q15833 Q53GF4
PDB IDs
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly MRNA Processing NcRNA Metabolic Process Cellular Component Assembly RNA Processing Gene Expression Spliceosomal Complex Assembly RNA Metabolic Process Histone MRNA Metabolic Process Regulation Of Exocytosis Regulation Of Insulin Secretion Termination Of RNA Polymerase II Transcription Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion Nucleobase-containing Compound Metabolic Process Leukocyte Degranulation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Long-term Synaptic Potentiation Regulation Of Secretion Vesicle Fusion Regulation Of Hormone Secretion Regulated Secretory Pathway Synaptic Vesicle Exocytosis Cell Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis DNA-templated Transcription, Termination Exocytosis Vesicle Docking Organelle Fusion MRNA 3'-end Processing Membrane Docking Nitrogen Compound Metabolic Process Positive Regulation Of Eosinophil Degranulation Histone H3-T6 Phosphorylation Post-Golgi Vesicle-mediated Transport Membrane Organization Regulation Of Vesicle-mediated Transport Regulation Of Protein Secretion RNA 3'-end Processing Eosinophil Degranulation Neurotransmitter Secretion	Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Fusion Cellular Component Assembly Synaptic Vesicle Exocytosis Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly Organelle Fusion MRNA Processing NcRNA Metabolic Process Neurotransmitter Secretion Synaptic Vesicle Transport MRNA Metabolic Process Membrane Fusion RNA Processing Regulation Of Neurotransmitter Levels Exocytosis Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle Docking Secretion By Cell Membrane Docking Secretion Establishment Of Organelle Localization Leukocyte Degranulation Calcium Ion-dependent Exocytosis Organelle Localization Membrane Organization Regulated Secretory Pathway Cell-cell Signaling Spliceosomal Complex Assembly Synaptic Transmission Positive Regulation Of Synaptic Transmission Protein Transport Vesicle-mediated Transport Histone MRNA Metabolic Process Establishment Of Protein Localization Regulation Of Exocytosis Leukocyte Activation Involved In Immune Response Glutamate Secretion Termination Of RNA Polymerase II Transcription Protein Localization Long-term Synaptic Potentiation Establishment Of Localization In Cell
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?