STXBP3 and SNRPD3

Number of citations of the paper that reports this interaction (PMID 12065586)
31

Data Source:
HPRD (in vivo)

		STXBP3	SNRPD3
Gene Name		syntaxin binding protein 3	small nuclear ribonucleoprotein D3 polypeptide 18kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Alpha Granule Specific Granule Extracellular Vesicular Exosome Tertiary Granule	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding	Protein Binding Enzyme Binding Poly(A) RNA Binding Histone Pre-mRNA DCP Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Brain Development Blood Coagulation Protein Transport Glucose Transport Protein To Membrane Docking Insulin Secretion Platelet Activation Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Protein Heterooligomerization Membrane Organization Platelet Aggregation	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process
Pathways		Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		14 interactors: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	27 interactors: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SNRPN SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77
Entrez ID		6814	6634
HPRD ID		10517	03039
Ensembl ID		ENSG00000116266
Uniprot IDs		O00186	B4DJP7 P62318
PDB IDs			1D3B 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3VRI
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly MRNA Processing NcRNA Metabolic Process Cellular Component Assembly RNA Processing Gene Expression Spliceosomal Complex Assembly RNA Metabolic Process Histone MRNA Metabolic Process Regulation Of Exocytosis Regulation Of Insulin Secretion Termination Of RNA Polymerase II Transcription Regulation Of Regulated Secretory Pathway Regulation Of Peptide Hormone Secretion Nucleobase-containing Compound Metabolic Process Leukocyte Degranulation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Long-term Synaptic Potentiation Regulation Of Secretion Vesicle Fusion Regulation Of Hormone Secretion Regulated Secretory Pathway Synaptic Vesicle Exocytosis Cell Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis DNA-templated Transcription, Termination Exocytosis Vesicle Docking Organelle Fusion MRNA 3'-end Processing Membrane Docking Nitrogen Compound Metabolic Process Positive Regulation Of Eosinophil Degranulation Histone H3-T6 Phosphorylation Post-Golgi Vesicle-mediated Transport Membrane Organization Regulation Of Vesicle-mediated Transport Regulation Of Protein Secretion RNA 3'-end Processing Eosinophil Degranulation Neurotransmitter Secretion	Spliceosomal SnRNP Assembly RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing Ribonucleoprotein Complex Assembly RNA Processing MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Cellular Macromolecular Complex Assembly RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Component Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Nitrogen Compound Metabolic Process Cellular Metabolic Process Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Neutrophil Degranulation Neutrophil Activation Involved In Immune Response DNA-templated Transcription, Termination MRNA 3'-end Processing RNA 3'-end Processing Response To Organic Substance Neutrophil Mediated Immunity Neutrophil Activation Cellular Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Metabolic Process Cell Activation Leukocyte Degranulation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Leukocyte Activation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Negative Regulation Of Glucocorticoid Secretion Blue Light Signaling Pathway
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?