DDX20 and NR0B2

Number of citations of the paper that reports this interaction (PubMedID 14963109)
0

Data Source:
HPRD (two hybrid)

		DDX20	NR0B2
Description		DEAD-box helicase 20	nuclear receptor subfamily 0 group B member 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Nuclear Body Transcription Repressor Complex SMN Complex Protein-containing Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Cajal Bodies	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Histone Deacetylase Binding DNA-binding Transcription Factor Binding	Transcription Corepressor Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding Protein Homodimerization Activity Nuclear Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding Transcription Regulator Inhibitor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Oogenesis Regulation Of Steroid Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Circadian Rhythm Cholesterol Metabolic Process Response To Glucose Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Animal Organ Regeneration Positive Regulation Of Insulin Secretion Circadian Regulation Of Gene Expression Negative Regulation Of DNA-binding Transcription Factor Activity Response To Ethanol Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Rhythmic Process
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068) LDL cholesterol ( 24097068) Triglycerides ( 24097068)
Interacting Genes		33 interacting genes: AGO2 APP CFTR CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53	51 interacting genes: AR CHRD CIDEC DDX20 EID1 ESR1 ESR2 ESRRA ESRRG FN1 GPS2 GPSM3 HDAC3 HDAC6 HNF4A HNF4G HNRNPA1 ID2 IL3RA NCOA3 NEUROD1 NR1H2 NR1H3 NR1I2 NR1I3 NR3C1 NR5A2 PAX9 PEF1 PLSCR1 POLR2A PPARD PPARG RARA RARG RBP5 RNF31 RXRA RXRB RXRG SMAD4 SMARCA2 SMARCB1 SMARCE1 SNW1 THRA TP53 VDR XBP1 ZAP70 ZMYND10
Entrez ID		11218	8431
HPRD ID		05859	05219
Ensembl ID		ENSG00000064703	ENSG00000131910
Uniprot IDs		Q9H4N4 Q9UHI6	Q15466
PDB IDs		2OXC 3B7G	1YUC 2Q3Y 2Z4J 4DOR 4ONI 5UFS 6W9M 7YXC 7YXD 7YXN 7YXO 7YXP 7YXR
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Protein-containing Complex Assembly U2 SnRNP Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex RNA Splicing U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP MRNA Processing U4/U6 X U5 Tri-snRNP Complex MRNA Metabolic Process U2-type Precatalytic Spliceosome Cellular Component Assembly SMN Complex RNA Processing Gemini Of Cajal Bodies Nucleoplasm MRNA Splicing, Via Spliceosome RNA Methylation Precatalytic Spliceosome Catalytic Step 2 Spliceosome RNA Binding Spliceosomal Complex Macromolecule Methylation RNA Metabolic Process RNA Modification Nucleus Nuclear Body Ribonucleoprotein Complex Methylation Protein-containing Complex Spliceosomal Tri-snRNP Complex Transcription Repressor Complex Nucleic Acid Metabolic Process Rhythmic Process Cytosol Histone Deacetylase Complex	Nuclear Receptor Activity Intracellular Receptor Signaling Pathway Hormone-mediated Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Retinoic Acid Receptor Signaling Pathway Chromatin Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Binding Nuclear Steroid Receptor Activity RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Regulation Of Gene Expression RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Nucleoplasm DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Cellular Developmental Process Cell Differentiation MRNA Transcription DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process
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