LZTS1 and RABIF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LZTS1	RABIF
Description		leucine zipper tumor suppressor 1	RAB interacting factor
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Cell Projection Dendritic Spine Synapse Glutamatergic Synapse	Cytosol Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Macroautophagy Regulation Of Synaptic Plasticity Regulation Of Dendrite Morphogenesis Regulation Of Postsynapse Assembly	Post-Golgi Vesicle-mediated Transport Small GTPase-mediated Signal Transduction Protein Transport Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Circulating myeloperoxidase levels (serum) ( 23620142) Dental caries ( 23064961 23259602) Femur bone mineral density x serum urate levels interaction ( 34046847) Influenza A (H1N1) infection ( 26379185) Interleukin-6 levels ( 33517400) Major depressive disorder (broad) ( 20038947) Persistent hepatitis B virus infection ( 27244555) Preeclampsia ( 23551011) Rheumatoid arthritis ( 30891314) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		100 interacting genes: AGTR1 AMOT AP1M1 BYSL CARD9 CCDC102B CCDC120 CCDC13 CCDC187 CCDC57 CCHCR1 CDC23 CDC25C CDC37 CDC7 CDK1 CEP83 CKS1B COG2 COPB1 CWF19L2 DDX6 DRC4 EEF1G ELOA ENKD1 EXOC8 FAM161A FAM161B FAM50B FAM81B FAM90A1 GARIN1B GOLGA1 GPKOW HMGB2 IDO2 KANK2 KAT5 KAZN KDM1A KIF9 KIFC3 LENG1 LMNB2 LMO1 LMO2 LMO3 LMO4 LNX1 LSM2 MAPK9 MCRS1 METTL21A MFAP1 MID2 MTCL2 NEK6 NTAQ1 PIBF1 PICK1 PLEKHA7 POLR1C POLR3C PPP1R18 PRKAB2 PRPF18 PRPF3 PSMA1 PSPC1 QARS1 RABIF RHPN1 RSPH14 RUNX1T1 SCNM1 SGF29 SPDYC SUFU SYT17 SYT6 SYTL4 TBC1D1 TBC1D7 TCEA2 TSGA10 TSGA10IP TTC9C TXLNA TXLNB TXNDC9 UBASH3A ZGPAT ZMYND19 ZNF250 ZNF3 ZNF35 ZNF417 ZNF572 ZNF587	27 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1B RAB3A RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544
Entrez ID		11178	5877
HPRD ID		05945	04566
Ensembl ID		ENSG00000061337	ENSG00000183155
Uniprot IDs		Q9Y250	P47224 Q53EV1
PDB IDs		8Y1U	1FWQ 2FU5
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton DNA-binding Transcription Factor Binding Centrosome Centriole Nucleoplasm Cilium Organization Microtubule Cytoskeleton Organization Zonula Adherens Maintenance Cytoplasm	Myosin V Binding GTPase Activity GTP Binding Integrin Complex Exocytosis GTP-dependent Protein Binding Integrin-mediated Signaling Pathway Cell-matrix Adhesion Cell-substrate Junction Assembly Secretion By Cell Cell-substrate Junction Organization Cell Junction Organization Synaptic Vesicle Positive Regulation Of Regulated Secretory Pathway Perinuclear Region Of Cytoplasm Secretory Vesicle Cell-cell Adhesion Cell-substrate Adhesion Secretion Skin Morphogenesis Cellular Component Maintenance Protein Transport G Protein Activity Intracellular Protein Localization Regulation Of Exocytosis Mesodermal Cell Differentiation Positive Regulation Of Exocytosis Laminin Binding Focal Adhesion Hydrolase Activity Establishment Of Protein Localization Signaling Receptor Activity Golgi Organization Cell Adhesion Mediated By Integrin Nucleotide Binding Response To Muscle Activity Regulation Of Regulated Secretory Pathway Metal Ion Binding Integrin Alpha6-beta4 Complex Regulation Of Vesicle-mediated Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Viral Process Integrin Binding Vesicle-mediated Transport Axonogenesis Cell Adhesion Integrin Alpha6-beta1 Complex Positive Regulation Of Epithelial Cell Migration Integrin Alpha3-beta1 Complex
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