LZTS1 and QARS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LZTS1	QARS1
Description		leucine zipper tumor suppressor 1	glutaminyl-tRNA synthetase 1
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Cell Projection Dendritic Spine Synapse Glutamatergic Synapse	Cytoplasm Mitochondrial Matrix Cytosol Aminoacyl-tRNA Synthetase Multienzyme Complex Protein-containing Complex
	Molecular Function	Protein Binding	Nucleotide Binding Aminoacyl-tRNA Ligase Activity Glutamine-tRNA Ligase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Ligase Activity Protein Kinase Binding
	Biological Process	Negative Regulation Of Macroautophagy Regulation Of Synaptic Plasticity Regulation Of Dendrite Morphogenesis Regulation Of Postsynapse Assembly	Translation TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Brain Development Negative Regulation Of Stress-activated MAPK Cascade TRNA Aminoacylation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Apoptotic Signaling Pathway
Pathways			Selenoamino acid metabolism Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS		Adult body size ( 32376654) Circulating myeloperoxidase levels (serum) ( 23620142) Dental caries ( 23064961 23259602) Femur bone mineral density x serum urate levels interaction ( 34046847) Influenza A (H1N1) infection ( 26379185) Interleukin-6 levels ( 33517400) Major depressive disorder (broad) ( 20038947) Persistent hepatitis B virus infection ( 27244555) Preeclampsia ( 23551011) Rheumatoid arthritis ( 30891314) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		100 interacting genes: AGTR1 AMOT AP1M1 BYSL CARD9 CCDC102B CCDC120 CCDC13 CCDC187 CCDC57 CCHCR1 CDC23 CDC25C CDC37 CDC7 CDK1 CEP83 CKS1B COG2 COPB1 CWF19L2 DDX6 DRC4 EEF1G ELOA ENKD1 EXOC8 FAM161A FAM161B FAM50B FAM81B FAM90A1 GARIN1B GOLGA1 GPKOW HMGB2 IDO2 KANK2 KAT5 KAZN KDM1A KIF9 KIFC3 LENG1 LMNB2 LMO1 LMO2 LMO3 LMO4 LNX1 LSM2 MAPK9 MCRS1 METTL21A MFAP1 MID2 MTCL2 NEK6 NTAQ1 PIBF1 PICK1 PLEKHA7 POLR1C POLR3C PPP1R18 PRKAB2 PRPF18 PRPF3 PSMA1 PSPC1 QARS1 RABIF RHPN1 RSPH14 RUNX1T1 SCNM1 SGF29 SPDYC SUFU SYT17 SYT6 SYTL4 TBC1D1 TBC1D7 TCEA2 TSGA10 TSGA10IP TTC9C TXLNA TXLNB TXNDC9 UBASH3A ZGPAT ZMYND19 ZNF250 ZNF3 ZNF35 ZNF417 ZNF572 ZNF587	158 interacting genes: ACTN2 ANXA7 APP ASL B9D2 BIRC7 BTG3 CCDC33 CDK4 CDKN1A CLTC COG6 CPNE3 CTBP2 DISC1 DNM2 DPPA4 DTX2 DUSP11 EDC3 EFHC2 ESS2 FAM118B FAM161A FAM83A GADD45A GPBP1 GSK3B GSTZ1 H2AX HES7 HMG20A HOXA1 IK IKZF1 IRF1 KCNE3 KLC3 KRT36 LAMTOR3 LGALS9B LGALS9C LNX1 LZTS1 LZTS2 MAP3K5 MCCD1 MESD MID2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR155 MIR15A MIR15B MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NAB2 NEBL NFKBID NLGN3 NOXA1 PICK1 PIK3R3 PIN1 PRDM6 PRRC2A PTPN21 RARS1 RBFOX2 REL RNF10 RNF11 SAXO4 SF3B4 SHLD1 SLA SMAD9 SMN1 SNCA SORBS3 SP7 SPATC1L SPDYE4 SPRED2 STK3 TADA2A TCF12 TGM7 TK1 TLE5 TRAF2 TRAF4 TRIM27 TRIM35 TRIP13 TSC22D1 TTR USHBP1 VPS37B XIAP ZMYND12
Entrez ID		11178	5859
HPRD ID		05945	07223
Ensembl ID		ENSG00000061337	ENSG00000172053
Uniprot IDs		Q9Y250	B7Z840 P47897
PDB IDs		8Y1U	4R3Z 4YE6 4YE8 4YE9
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton DNA-binding Transcription Factor Binding Centrosome Centriole Nucleoplasm Cilium Organization Microtubule Cytoskeleton Organization Zonula Adherens Maintenance Cytoplasm	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cytokine Production MRNA Destabilization RNA Destabilization Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Motility Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of Locomotion Regulation Of MRNA Stability Negative Regulation Of Developmental Process Regulation Of Angiogenesis Regulation Of RNA Stability Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Vasculature Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Translation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Cytokine Production Regulation Of Developmental Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?