LZTS1 and LMNB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LZTS1	LMNB2
Description		leucine zipper tumor suppressor 1	lamin B2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Cell Projection Dendritic Spine Synapse Glutamatergic Synapse	Nucleus Nuclear Envelope Nuclear Lamina Intermediate Filament Nuclear Membrane
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Macroautophagy Regulation Of Synaptic Plasticity Regulation Of Dendrite Morphogenesis Regulation Of Postsynapse Assembly	Nuclear Envelope Organization Cytoskeleton Organization Nuclear Migration Heterochromatin Formation Nuclear Pore Localization Protein Localization To Nuclear Envelope
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Circulating myeloperoxidase levels (serum) ( 23620142) Dental caries ( 23064961 23259602) Femur bone mineral density x serum urate levels interaction ( 34046847) Influenza A (H1N1) infection ( 26379185) Interleukin-6 levels ( 33517400) Major depressive disorder (broad) ( 20038947) Persistent hepatitis B virus infection ( 27244555) Preeclampsia ( 23551011) Rheumatoid arthritis ( 30891314) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		100 interacting genes: AGTR1 AMOT AP1M1 BYSL CARD9 CCDC102B CCDC120 CCDC13 CCDC187 CCDC57 CCHCR1 CDC23 CDC25C CDC37 CDC7 CDK1 CEP83 CKS1B COG2 COPB1 CWF19L2 DDX6 DRC4 EEF1G ELOA ENKD1 EXOC8 FAM161A FAM161B FAM50B FAM81B FAM90A1 GARIN1B GOLGA1 GPKOW HMGB2 IDO2 KANK2 KAT5 KAZN KDM1A KIF9 KIFC3 LENG1 LMNB2 LMO1 LMO2 LMO3 LMO4 LNX1 LSM2 MAPK9 MCRS1 METTL21A MFAP1 MID2 MTCL2 NEK6 NTAQ1 PIBF1 PICK1 PLEKHA7 POLR1C POLR3C PPP1R18 PRKAB2 PRPF18 PRPF3 PSMA1 PSPC1 QARS1 RABIF RHPN1 RSPH14 RUNX1T1 SCNM1 SGF29 SPDYC SUFU SYT17 SYT6 SYTL4 TBC1D1 TBC1D7 TCEA2 TSGA10 TSGA10IP TTC9C TXLNA TXLNB TXNDC9 UBASH3A ZGPAT ZMYND19 ZNF250 ZNF3 ZNF35 ZNF417 ZNF572 ZNF587	28 interacting genes: AMOT AMOTL2 CA8 CCDC120 CCDC88B CDC37 EFHC2 FH GOLGA2 LZTS1 MFAP1 MID2 OVOL1 PIBF1 POU6F2 PPP1R13B PRKCD SVIL TFIP11 THAP1 TMPO TP53BP2 TRIM27 TSGA10IP USP2 WASHC3 ZC2HC1C ZFHX3
Entrez ID		11178	84823
HPRD ID		05945	01037
Ensembl ID		ENSG00000061337	ENSG00000176619
Uniprot IDs		Q9Y250	Q03252
PDB IDs		8Y1U	2LLL
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton DNA-binding Transcription Factor Binding Centrosome Centriole Nucleoplasm Cilium Organization Microtubule Cytoskeleton Organization Zonula Adherens Maintenance Cytoplasm	Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Regulation Of Actin Filament Organization Cytoplasm Regulation Of Autophagy Regulation Of Actin Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament-based Process Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription
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