DSTN and TAX1BP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DSTN	TAX1BP1
Gene Name		destrin (actin depolymerizing factor)	Tax1 (human T-cell leukemia virus type I) binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Vesicular Exosome	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Actin Binding	Protein Binding Kinase Binding
	Biological Process	Movement Of Cell Or Subcellular Component Actin Polymerization Or Depolymerization Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Actin Filament Severing	Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS		Presence of antiphospholipid antibodies ( 23509613)
Protein-Protein Interactions		8 interactors: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2	40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC
Entrez ID		11034	8887
HPRD ID		16446	05618
Ensembl ID		ENSG00000125868	ENSG00000106052
Uniprot IDs		P60981	A4D196 B4DSG5 Q86VP1
PDB IDs
Enriched GO Terms of Interacting Partners?		Adherens Junction Organization Actin Cytoskeleton Organization Cell Junction Assembly Actin Filament-based Process Cell-cell Junction Organization Platelet Aggregation Sarcomere Organization Retina Homeostasis Myofibril Assembly Cytoskeleton Organization Primary Spermatocyte Growth Midbrain Development Nervous System Development Ephrin Receptor Signaling Pathway Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Actomyosin Structure Organization Generation Of Neurons Striated Muscle Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neurogenesis Muscle Cell Development Anatomical Structure Development Tissue Homeostasis Organelle Organization Platelet Activation Cell Development Innate Immune Response Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cellular Component Assembly Cell Differentiation Striated Muscle Cell Differentiation Mullerian Duct Regression Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Homeostasis Developmental Process Cellular Response To ATP Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Positive Regulation Of Actin Filament Depolymerization Muscle Cell Differentiation Regulation Of Cellular Component Size Homotypic Cell-cell Adhesion System Development Single Organism Reproductive Process	Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization
Tagcloud ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Difference) ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Intersection) ?