DSTN and SSH1

Number of citations of the paper that reports this interaction (PMID 11832213)
123

Data Source:
BioGRID (enzymatic study)

		DSTN	SSH1
Gene Name		destrin (actin depolymerizing factor)	slingshot protein phosphatase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Midbody Cleavage Furrow
	Molecular Function	Actin Binding	DNA Binding Actin Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Movement Of Cell Or Subcellular Component Actin Polymerization Or Depolymerization Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Actin Filament Severing	Cell Morphogenesis Protein Dephosphorylation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Lamellipodium Assembly Actin Cytoskeleton Organization Regulation Of Cellular Protein Metabolic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Axonogenesis Cellular Response To ATP
Pathways
Drugs
Diseases
GWAS		Presence of antiphospholipid antibodies ( 23509613)
Protein-Protein Interactions		8 interactors: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2	5 interactors: ACTB CFL1 CFL2 CORO1B DSTN
Entrez ID		11034	54434
HPRD ID		16446	09486
Ensembl ID		ENSG00000125868	ENSG00000084112
Uniprot IDs		P60981	Q8WYL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Adherens Junction Organization Actin Cytoskeleton Organization Cell Junction Assembly Actin Filament-based Process Cell-cell Junction Organization Platelet Aggregation Sarcomere Organization Retina Homeostasis Myofibril Assembly Cytoskeleton Organization Primary Spermatocyte Growth Midbrain Development Nervous System Development Ephrin Receptor Signaling Pathway Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Actomyosin Structure Organization Generation Of Neurons Striated Muscle Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neurogenesis Muscle Cell Development Anatomical Structure Development Tissue Homeostasis Organelle Organization Platelet Activation Cell Development Innate Immune Response Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cellular Component Assembly Cell Differentiation Striated Muscle Cell Differentiation Mullerian Duct Regression Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Homeostasis Developmental Process Cellular Response To ATP Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Positive Regulation Of Actin Filament Depolymerization Muscle Cell Differentiation Regulation Of Cellular Component Size Homotypic Cell-cell Adhesion System Development Single Organism Reproductive Process	Positive Regulation Of Actin Filament Depolymerization Actin Filament Depolymerization Positive Regulation Of Protein Depolymerization Positive Regulation Of Protein Complex Disassembly Actin Filament Organization Regulation Of Actin Filament Depolymerization Regulation Of Actin Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Actin Filament-based Process Regulation Of Protein Depolymerization Regulation Of Cytoskeleton Organization Regulation Of Protein Complex Disassembly Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Disassembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Protein Complex Disassembly Regulation Of Actin Filament Length Regulation Of Organelle Organization Regulation Of Dendritic Spine Morphogenesis Cytoskeleton Organization Regulation Of Cellular Component Size Regulation Of Dendritic Spine Development Organelle Organization Positive Regulation Of Organelle Organization Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Dendrite Morphogenesis Wound Healing Chemotaxis Ephrin Receptor Signaling Pathway Regulation Of Dendrite Development Regulation Of Cellular Component Organization Response To Wounding Protein Localization To Cell Leading Edge Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ameboidal-type Cell Migration Positive Regulation Of Lamellipodium Morphogenesis Platelet Activation Actin Filament Branching Cell Projection Organization Phagocytosis Fc Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway
Tagcloud ?			10mum 20days aging cofilin1 compartments cytoskeleton decline dysregulation inactivation interestingly knock lim limk1 mef mefdko occurring pcns plasticity presenilin ps1 regard remodeling rescued safely secretase shed shh1 slingshot stream
Tagcloud (Difference) ?			10mum 20days aging cofilin1 compartments cytoskeleton decline dysregulation inactivation interestingly knock lim limk1 mef mefdko occurring pcns plasticity presenilin ps1 regard remodeling rescued safely secretase shed shh1 slingshot stream
Tagcloud (Intersection) ?