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DSTN and ACTG1
Number of citations of the paper that reports this interaction (PMID
8399167
)
67
Data Source:
HPRD
(in vitro)
DSTN
ACTG1
Gene Name
destrin (actin depolymerizing factor)
actin gamma 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Actin Cytoskeleton
Cortical Actin Cytoskeleton
Extracellular Vesicular Exosome
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Plasma Membrane
Membrane
Myofibril
Filamentous Actin
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Biological Process
Movement Of Cell Or Subcellular Component
Actin Polymerization Or Depolymerization
Actin Filament Depolymerization
Positive Regulation Of Actin Filament Depolymerization
Actin Filament Severing
Retina Homeostasis
Movement Of Cell Or Subcellular Component
Axon Guidance
Cell Junction Assembly
Adherens Junction Organization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Sarcomere Organization
Cell-cell Junction Organization
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Membrane Organization
Platelet Aggregation
Pathways
Axon guidance
Gap junction degradation
Adherens junctions interactions
Translocation of GLUT4 to the plasma membrane
L1CAM interactions
Recycling pathway of L1
VEGFA-VEGFR2 Pathway
EPHB-mediated forward signaling
Interaction between L1 and Ankyrins
Cell-cell junction organization
EPH-ephrin mediated repulsion of cells
Gap junction trafficking and regulation
EPH-Ephrin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Cell junction organization
Formation of annular gap junctions
Gap junction trafficking
Signaling by VEGF
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Presence of antiphospholipid antibodies (
23509613
)
Protein-Protein Interactions
8 interactors:
ACTB
ACTG1
CFL2
SHBG
SMAD9
SSH1
TAX1BP1
TESK2
60 interactors:
ABLIM1
ACTB
ANXA5
APOE
ATF7IP
BCAP31
BRCA1
CAP1
CAP2
CAPZA3
CCDC22
CDKN2A
CFL1
CFL2
COTL1
CTBP2
CTTN
CYBB
DISC1
DNASE1
DSTN
DYNLL1
EHHADH
EIF6
FHOD1
FPR1
GIT2
GSN
GZMA
GZMK
LGALS13
LIG4
LSP1
MAP1A
MAPK6
MYO1A
MYOC
NDRG1
NR3C2
PFN2
PLD1
PLEC
PPP1R9A
PRSS23
PSEN2
PTPRO
RPS6KA5
SCIN
SH3GL2
ST3GAL3
SUMO4
TMSB4X
TMSB4Y
TNIK
VASP
VIL1
WASF1
WASL
WDYHV1
WIPF1
Entrez ID
11034
71
HPRD ID
16446
00017
Ensembl ID
ENSG00000125868
ENSG00000184009
Uniprot IDs
P60981
P63261
PDB IDs
Enriched GO Terms of Interacting Partners
?
Adherens Junction Organization
Actin Cytoskeleton Organization
Cell Junction Assembly
Actin Filament-based Process
Cell-cell Junction Organization
Platelet Aggregation
Sarcomere Organization
Retina Homeostasis
Myofibril Assembly
Cytoskeleton Organization
Primary Spermatocyte Growth
Midbrain Development
Nervous System Development
Ephrin Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Actomyosin Structure Organization
Generation Of Neurons
Striated Muscle Cell Development
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Neurogenesis
Muscle Cell Development
Anatomical Structure Development
Tissue Homeostasis
Organelle Organization
Platelet Activation
Cell Development
Innate Immune Response
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Cellular Component Assembly
Cell Differentiation
Striated Muscle Cell Differentiation
Mullerian Duct Regression
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Homeostasis
Developmental Process
Cellular Response To ATP
Phagocytosis
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Cell Morphogenesis
Positive Regulation Of Actin Filament Depolymerization
Muscle Cell Differentiation
Regulation Of Cellular Component Size
Homotypic Cell-cell Adhesion
System Development
Single Organism Reproductive Process
Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Cellular Component Organization
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Actin Cytoskeleton Organization
Positive Regulation Of Cytoskeleton Organization
Actin Polymerization Or Depolymerization
Regulation Of Cytoskeleton Organization
Actin Filament-based Process
Actin Filament Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Organelle Organization
Organelle Organization
Regulation Of Cellular Component Size
Chemotaxis
Cell Projection Organization
Neurogenesis
Negative Regulation Of Cytoskeleton Organization
Regulation Of Actin Filament Depolymerization
Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Polymerization
Negative Regulation Of Actin Filament Polymerization
Negative Regulation Of Protein Complex Assembly
Neuron Projection Development
Negative Regulation Of Protein Polymerization
Movement Of Cell Or Subcellular Component
Axon Guidance
Generation Of Neurons
Actin Filament Severing
Positive Regulation Of Cellular Component Biogenesis
Locomotion
Regulation Of Protein Depolymerization
Cell Development
Response To External Stimulus
Neuron Development
Nervous System Development
Axon Development
Regulation Of Protein Complex Disassembly
Regulation Of Cell Projection Organization
Actin Filament Depolymerization
Neuron Projection Morphogenesis
Axonogenesis
Neuron Differentiation
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Actin Filament Polymerization
Signal Transduction
Tagcloud
?
alteration
birc7
chrcc
chromophobe
cpq
distinctions
ectopic
enabled
exome
faah2
fusions
met
mitf
mutated
nccrccs
nf2
oncocytoma
oncocytomas
papillary
pdhb
pdxdc1
pnkd
prcc
rcc
slc5a3
transcriptome
trcc
unreported
znf765
Tagcloud (Difference)
?
alteration
birc7
chrcc
chromophobe
cpq
distinctions
ectopic
enabled
exome
faah2
fusions
met
mitf
mutated
nccrccs
nf2
oncocytoma
oncocytomas
papillary
pdhb
pdxdc1
pnkd
prcc
rcc
slc5a3
transcriptome
trcc
unreported
znf765
Tagcloud (Intersection)
?