CWC25

Name	CWC25 spliceosome associated protein
Structure
Novel Interactors	1 novel interactors: GSDMB
Interactors	7 interactors: CCDC85B FMR1 KRT34 LAMC3 MDM2 OGT TRIM21
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 1 Spliceosome
	Molecular Function	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways	mRNA Splicing - Major Pathway
GWAS	Intraocular pressure ( 29617998 )
Entrez ID	54883
HPRD ID	07892
Ensembl ID	ENSG00000273559
Uniprot IDs	Q9NXE8
PDB IDs	5YZG 6ZYM 8I0W
GO Terms Enriched among Interactors ?	Pyroptotic Inflammatory Response Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Viral Life Cycle Negative Regulation Of Protein Metabolic Process Stress Granule Assembly Cellular Response To Nutrient Negative Regulation Of Translational Initiation Membraneless Organelle Assembly Positive Regulation Of Viral Process Positive Regulation Of Intracellular Transport Of Viral Material Response To Formaldehyde Protein Autoubiquitination Cellular Response To Vitamin B1 Protein Destabilization Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Protein Catabolic Process Regulation Of Receptor Internalization Regulation Of Proteolysis Cytoplasmic Stress Granule Negative Regulation Of Post-translational Protein Modification Dendritic Filopodium Histone H3 Reader Activity Cytotoxic T Cell Pyroptotic Cell Death Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Long-term Synaptic Depression Regulation Of Viral Life Cycle Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Translational Initiation Response To Vitamin B1 Response To Water-immersion Restraint Stress Cellular Response To Actinomycin D Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Viral Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process NEDD8 Ligase Activity Response To Actinomycin D Negative Regulation Of Proteolysis Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Inflammatory Response Negative Regulation Of Protein Deubiquitination Response To Nutrient RNA Strand Annealing Activity Regulation Of Neuronal Action Potential