TMED2 and COPA

Number of citations of the paper that reports this interaction (PMID 8703076)
92

Data Source:
HPRD (in vitro)

		TMED2	COPA
Gene Name		transmembrane emp24 domain trafficking protein 2	coatomer protein complex, subunit alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Cytoplasm Cytosol Membrane COPI Vesicle Coat Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Hormone Activity Structural Molecule Activity
	Biological Process	Maternal Placenta Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Negative Regulation Of GTPase Activity Cargo Loading Into Vesicle COPI Coating Of Golgi Vesicle COPII Vesicle Coating Embryonic Morphogenesis Protein Targeting To Plasma Membrane	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Pancreatic Juice Secretion COPI Coating Of Golgi Vesicle Membrane Organization
Pathways		Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing	COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10	12 interactors: ARCN1 ARFGAP1 COPB2 COPE COPZ1 MTNR1B PDGFRB SACM1L SLC25A11 STX8 TMED10 TMED2
Entrez ID		10959	1314
HPRD ID		17984	03564
Ensembl ID		ENSG00000086598	ENSG00000122218
Uniprot IDs		Q15363 Q6FHT8	P53621
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Protein Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Intracellular Transport Membrane Organization Intracellular Protein Transport Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Cellular Localization Vesicle-mediated Transport Organelle Organization Golgi Organization Transport Endomembrane System Organization ER To Golgi Vesicle-mediated Transport Secretion Activation Of Ral GTPase Activity Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Positive Regulation Of Glucose Import In Response To Insulin Stimulus Mitotic Cell Cycle Positive Regulation Of Ral GTPase Activity Regulation Of Ral Protein Signal Transduction Pancreatic Juice Secretion Cargo Loading Into Vesicle Negative Regulation Of Dendrite Morphogenesis Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Vesicle Fusion Positive Regulation Of Glycogen Biosynthetic Process Peripheral Nervous System Myelin Maintenance Negative Regulation Of Dendrite Development Long Term Synaptic Depression Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Cellular Copper Ion Homeostasis COPII Vesicle Coating	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Organelle Organization Intra-Golgi Vesicle-mediated Transport Cellular Localization Cargo Loading Into Vesicle ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating COPII-coated Vesicle Budding Transport Cytoplasmic Transport Cell Migration Involved In Coronary Angiogenesis Cerebellar Purkinje Cell Layer Maturation Metanephric Mesenchymal Cell Migration Golgi Organization Angiogenesis Involved In Coronary Vascular Morphogenesis Cell Migration Involved In Kidney Development Alpha-ketoglutarate Transport Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Smooth Muscle Cell Chemotaxis Cerebellum Maturation Metanephric Comma-shaped Body Morphogenesis Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Cell Migration Involved In Vasculogenesis Metanephric S-shaped Body Morphogenesis Glomerular Mesangial Cell Proliferation Positive Regulation Of Metanephric Mesenchymal Cell Migration Comma-shaped Body Morphogenesis
Tagcloud ?		androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular	atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur
Tagcloud (Difference) ?		androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular	atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur
Tagcloud (Intersection) ?