TMED2 and GORASP2

Number of citations of the paper that reports this interaction (PMID 11739402)
23

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TMED2	GORASP2
Gene Name		transmembrane emp24 domain trafficking protein 2	golgi reassembly stacking protein 2, 55kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Maternal Placenta Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Negative Regulation Of GTPase Activity Cargo Loading Into Vesicle COPI Coating Of Golgi Vesicle COPII Vesicle Coating Embryonic Morphogenesis Protein Targeting To Plasma Membrane	Mitotic Cell Cycle Organelle Organization
Pathways		Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Protein-Protein Interactions		9 interactors: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10	69 interactors: AAMDC ACY3 AES APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148
Entrez ID		10959	26003
HPRD ID		17984	08303
Ensembl ID		ENSG00000086598	ENSG00000115806
Uniprot IDs		Q15363 Q6FHT8	B4DKT0 B4DNR1 Q9H8Y8
PDB IDs			3RLE 4EDJ
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Protein Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Intracellular Transport Membrane Organization Intracellular Protein Transport Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Cellular Localization Vesicle-mediated Transport Organelle Organization Golgi Organization Transport Endomembrane System Organization ER To Golgi Vesicle-mediated Transport Secretion Activation Of Ral GTPase Activity Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Positive Regulation Of Glucose Import In Response To Insulin Stimulus Mitotic Cell Cycle Positive Regulation Of Ral GTPase Activity Regulation Of Ral Protein Signal Transduction Pancreatic Juice Secretion Cargo Loading Into Vesicle Negative Regulation Of Dendrite Morphogenesis Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Vesicle Fusion Positive Regulation Of Glycogen Biosynthetic Process Peripheral Nervous System Myelin Maintenance Negative Regulation Of Dendrite Development Long Term Synaptic Depression Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Cellular Copper Ion Homeostasis COPII Vesicle Coating	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Golgi Organization Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of MAP Kinase Activity Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cargo Loading Into Vesicle Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Protein Transport Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Establishment Of Protein Localization Intracellular Protein Transport Regulation Of Protein Homodimerization Activity Regulation Of MAPK Cascade TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway COPII-coated Vesicle Budding Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor 3 Signaling Pathway Establishment Of Localization In Cell Regulation Of Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Protein Complex Assembly Positive Regulation Of Protein Metabolic Process Protein Homooligomerization Toll-like Receptor 4 Signaling Pathway Cell Death Death Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Positive Regulation Of Transferase Activity Cellular Localization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Protein Ubiquitination Intracellular Transport Negative Regulation Of Programmed Cell Death Negative Regulation Of Transferase Activity Protein Oligomerization Endomembrane System Organization Cell Cycle Cellular Protein Localization
Tagcloud ?		androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular
Tagcloud (Difference) ?		androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular
Tagcloud (Intersection) ?