TMED2

Description		transmembrane p24 trafficking protein 2
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle Cytoplasmic Vesicle Membrane COPI-coated Vesicle Membrane Cytoplasmic Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane
	Molecular Function	Frizzled Binding Smoothened Binding Protein Binding
	Biological Process	In Utero Embryonic Development Somitogenesis Neural Tube Closure Embryonic Placenta Development Maternal Placenta Development Heart Looping Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Inflammatory Response Endoplasmic Reticulum Organization Golgi Organization Intracellular Protein Localization Protein Secretion Positive Regulation Of Gene Expression Protein Transport Vesicle-mediated Transport Somite Rostral/caudal Axis Specification Negative Regulation Of GTPase Activity Multicellular Organism Growth Vesicle Cargo Loading Post-anal Tail Morphogenesis PERK-mediated Unfolded Protein Response Negative Regulation Of Smoothened Signaling Pathway COPI Coating Of Golgi Vesicle COPII Vesicle Coating Embryonic Morphogenesis Branching Involved In Labyrinthine Layer Morphogenesis Labyrinthine Layer Blood Vessel Development Chorion Development Maintenance Of Protein Localization In Organelle Protein Localization To Plasma Membrane Endoplasmic Reticulum Membrane Organization Negative Regulation Of Protein Localization To Plasma Membrane Allantois Development Regulation Of SREBP Signaling Pathway
Pathways		Pre-NOTCH Processing in Golgi COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10
Entrez ID		10959
HPRD ID		17984
Ensembl ID		ENSG00000086598
Uniprot IDs		Q15363 Q6FHT8
PDB IDs		5AZW
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Golgi Membrane Cis-Golgi Network Cellular Localization Intracellular Protein Localization Protein Transport Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Apparatus Vesicle-mediated Transport Golgi Vesicle Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Golgi Ribbon Formation COPI-coated Vesicle Intracellular Protein Transport Vesicle Cargo Loading Vesicle Budding From Membrane Intracellular Transport COPII-coated ER To Golgi Transport Vesicle Membrane Organization Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Syntaxin Binding Establishment Of Protein Localization To Plasma Membrane ER To Golgi Transport Vesicle Membrane Cellular Response To High Light Intensity Establishment Of Localization In Cell Mitotic Cleavage Furrow Ingression Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Response To High Light Intensity Retinal Rod Cell Apoptotic Process Cleavage Furrow Ingression Transport Vesicle Endoplasmic Reticulum Membrane Positive Regulation Of Cap-dependent Translational Initiation Localization Within Membrane Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Protein Localization To Cell Leading Edge Positive Regulation Of Protein Glycosylation Vesicle Targeting, To, From Or Within Golgi Pancreatic Juice Secretion COPII-coated Vesicle Budding Positive Regulation Of Cytoplasmic Translational Initiation Golgi Disassembly COPI Coating Of Golgi Vesicle Retinal Cell Apoptotic Process Regulation Of Protein Glycosylation Gamma-secretase Complex Membrane
Tagcloud ?