TMED2 and GORASP1

Number of citations of the paper that reports this interaction (PMID 11739402)
23

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TMED2	GORASP1
Gene Name		transmembrane emp24 domain trafficking protein 2	golgi reassembly stacking protein 1, 65kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Golgi Apparatus
	Molecular Function	Protein Binding
	Biological Process	Maternal Placenta Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Negative Regulation Of GTPase Activity Cargo Loading Into Vesicle COPI Coating Of Golgi Vesicle COPII Vesicle Coating Embryonic Morphogenesis Protein Targeting To Plasma Membrane	Mitotic Cell Cycle Golgi Organization Protein Transport Negative Regulation Of Dendrite Morphogenesis
Pathways		Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10	14 interactors: AGPS CASP3 CASP7 CDK1 GOLGA2 HIPK3 LONRF1 MAPK6 PLK1 PRKD2 SCRN1 TGFA TMED2 TMED3
Entrez ID		10959	64689
HPRD ID		17984	06038
Ensembl ID		ENSG00000086598	ENSG00000114745
Uniprot IDs		Q15363 Q6FHT8	B3KPY8 B4E1H8 Q9BQQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Protein Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Intracellular Transport Membrane Organization Intracellular Protein Transport Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Cellular Localization Vesicle-mediated Transport Organelle Organization Golgi Organization Transport Endomembrane System Organization ER To Golgi Vesicle-mediated Transport Secretion Activation Of Ral GTPase Activity Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Positive Regulation Of Glucose Import In Response To Insulin Stimulus Mitotic Cell Cycle Positive Regulation Of Ral GTPase Activity Regulation Of Ral Protein Signal Transduction Pancreatic Juice Secretion Cargo Loading Into Vesicle Negative Regulation Of Dendrite Morphogenesis Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Vesicle Fusion Positive Regulation Of Glycogen Biosynthetic Process Peripheral Nervous System Myelin Maintenance Negative Regulation Of Dendrite Development Long Term Synaptic Depression Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Cellular Copper Ion Homeostasis COPII Vesicle Coating	Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Kinase Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Proteolysis Protein Localization To Chromosome Positive Regulation Of Catalytic Activity Regulation Of Cell Death Negative Regulation Of Cell Death G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly Cell Death Death Negative Regulation Of Protein Kinase Activity Positive Regulation Of Mitotic Nuclear Division Nuclear Envelope Disassembly Negative Regulation Of Kinase Activity Peptidyl-threonine Phosphorylation Regulation Of MAPK Cascade Regulation Of Proteolysis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of MAP Kinase Activity Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Pronuclear Fusion Positive Regulation Of Protein Phosphorylation Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Transferase Activity Protein Phosphorylation Nuclear Envelope Organization Negative Regulation Of Protein Phosphorylation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Execution Phase Of Apoptosis
Tagcloud ?		androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular	adc aldh1l1 ankrd28 bhlhe40 cggbp1 ctdspl ephb1 fbln2 fgd5 foxp1 gnai2 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a
Tagcloud (Difference) ?		androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular	adc aldh1l1 ankrd28 bhlhe40 cggbp1 ctdspl ephb1 fbln2 fgd5 foxp1 gnai2 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a
Tagcloud (Intersection) ?