GIPC1 and SEMA4C

Number of citations of the paper that reports this interaction (PMID 10318831)
24

Data Source:
HPRD (in vitro, in vivo)

		GIPC1	SEMA4C
Gene Name		GIPC PDZ domain containing family, member 1	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Brush Border Cell Cortex Synaptic Vesicle Vesicle Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Endocytic Vesicle Dendritic Spine Dendritic Shaft Extracellular Vesicular Exosome	Extracellular Space Postsynaptic Density Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane Postsynaptic Membrane
	Molecular Function	Actin Binding Receptor Binding Protein Binding Myosin Binding PDZ Domain Binding Protein Homodimerization Activity	Receptor Activity
	Biological Process	Protein Targeting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Endothelial Cell Migration Regulation Of Synaptic Plasticity	Neural Tube Closure Cell Migration In Hindbrain Cerebellum Development Positive Regulation Of Stress-activated MAPK Cascade Muscle Cell Differentiation Semaphorin-plexin Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: ACTN1 ADRB1 CD93 DDIT3 DRD2 DRD3 FZD3 GSK3B IGF1R ITGA5 ITGA6 KIF1B LHCGR LRP1 LRP2 LRP8 MYO6 NRP1 NTRK1 NTRK2 RGS1 RGS19 SDC4 SEMA4B SEMA4C SLC2A1 TGFBR3 TPBG TYRP1 ZFPM1 ZNF408	11 interactors: DLG1 DLG2 DLG3 DLG4 GIPC1 KRT31 KRT40 NCDN NOTCH2NL PNMA1 RCHY1
Entrez ID		10755	54910
HPRD ID		05462	07257
Ensembl ID		ENSG00000123159	ENSG00000168758
Uniprot IDs		A8K2I7 O14908	Q9C0C4
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To External Stimulus Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Positive Regulation Of Phosphorylation Response To Abiotic Stimulus Cell Surface Receptor Signaling Pathway Cell Communication System Development Regulation Of CAMP Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Anatomical Structure Development Positive Regulation Of Metabolic Process Developmental Process Cognition Regulation Of CAMP Metabolic Process Signaling Regulation Of Signal Transduction Signal Transduction Multicellular Organismal Development Movement Of Cell Or Subcellular Component Cell Differentiation Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Learning Or Memory Cell Migration Negative Regulation Of Signal Transduction Activation Of Adenylate Cyclase Activity Anatomical Structure Morphogenesis Regulation Of Cell Development Response To Radiation Tissue Development Cellular Response To Stimulus Regulation Of Synaptic Transmission Cell Motility Regulation Of Apoptotic Process Negative Regulation Of Signaling Positive Regulation Of Adenylate Cyclase Activity Organ Development Response To Stimulus Response To Wounding Positive Regulation Of Cell Development Cell Morphogenesis Involved In Differentiation Response To Light Stimulus Positive Regulation Of Protein Phosphorylation Regulation Of Cell Death Locomotion Regulation Of Cell Differentiation Nervous System Development	Receptor Localization To Synapse Protein Localization To Synapse Receptor Clustering Nucleotide Phosphorylation Establishment Or Maintenance Of Apical/basal Cell Polarity Synaptic Transmission Protein Localization To Membrane Cell-cell Signaling Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Synaptic Plasticity Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Nucleotide Metabolic Process Cortical Cytoskeleton Organization Nucleobase-containing Small Molecule Metabolic Process Cellular Protein Localization Regulation Of Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Neuron Projection Development Negative Regulation Of Phosphatase Activity Membrane Organization Negative Regulation Of Dephosphorylation Neuron Development Axon Guidance Organophosphate Metabolic Process Protein Localization Regulation Of Phosphatase Activity Neuron Differentiation Cell Projection Organization Axonogenesis Locomotion Regulation Of Dephosphorylation Nervous System Development Axon Development Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cellular Localization Neuron Projection Morphogenesis T Cell Cytokine Production Developmental Process Movement Of Cell Or Subcellular Component Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Generation Of Neurons Cell Morphogenesis Involved In Differentiation Maintenance Of Apical/basal Cell Polarity Regulation Of Proteasomal Protein Catabolic Process Neurogenesis
Tagcloud ?		adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc2 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2	apart b1 b3 basement bidirectional capability fluids grouped heterodimer highlighting intriguing nkyimbeng played plexin plexins sema5a semaphorin semaphorines singaling subclasses takwi talk ultimate vertebrates yukawa
Tagcloud (Difference) ?		adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc2 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 tgfbetar3 vangl2	apart b1 b3 basement bidirectional capability fluids grouped heterodimer highlighting intriguing nkyimbeng played plexin plexins sema5a semaphorin semaphorines singaling subclasses takwi talk ultimate vertebrates yukawa
Tagcloud (Intersection) ?		sema4c