SEMA4C and PNMA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEMA4C	PNMA1
Description		semaphorin 4C	PNMA family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Postsynaptic Density Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse	Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity	Protein Binding
	Biological Process	Neural Crest Cell Migration Neural Tube Closure Nervous System Development Axon Guidance Cell Migration In Hindbrain Cerebellum Development Cell Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Muscle Cell Differentiation Negative Chemotaxis Semaphorin-plexin Signaling Pathway Regulation Of Postsynapse Assembly	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		20 interacting genes: CYSRT1 DLG1 DLG2 DLG3 DLG4 GIPC1 HSF2BP KRT16 KRT27 KRT31 KRT34 KRT40 KRTAP6-3 NBPF19 NCDN NOTCH2NLA PNMA1 RCHY1 TRIM54 USHBP1	170 interacting genes: ABHD17A AGTR1 AIRIM ANKRD36BP1 APTX ARHGEF6 ARID5A ASMTL ATP5PO ATP6V1G1 ATXN7 BEX2 BYSL C21orf58 C8orf33 CARHSP1 CBX8 CCDC146 CCDC187 CCDC198 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CFTR CHIC2 CHMP2B CNNM3 COX5B CTNNA3 DAXX DCTN4 EAF2 EHHADH ENKD1 FAM107A FAM110A FAM161A FAM161B FBF1 FBXL18 FEM1C FMNL2 FOXD4L1 FOXD4L3 FXR1 FXR2 GADD45GIP1 GATA1 GEM GPANK1 GPR25 GRAP2 GTPBP10 HAPLN2 HCK HDAC4 HGS HNRNPLL HOXB9 IGFN1 INO80B IVD KANSL1 KAT2B LAGE3 LENG1 LIN37 LMO3 LNX1 LSM2 MAB21L2 MACIR MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 MYO15B MYOZ1 NIF3L1 NPBWR2 NSMF NTAQ1 NUDT16L1 PARD3 PARD6B PCGF6 PER1 PIN1 PIN4 PKN1 PKN3 PNMA5 PNMA6A POLDIP3 POLL POLM PRKAB2 PRKCG PRKCI PRPF18 PRPF31 PSMA1 RAD51D RAPGEF3 RBM41 RPP25 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHC3 SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 SSX2IP STAMBPL1 SUV39H2 TASOR2 TCEA2 TCEANC TCL1B TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRIM73 TRPV6 TSHZ2 TSPYL4 TTC23 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 VPS9D1 WDR25 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF148 ZNF35 ZNF410 ZNF438 ZNF564 ZNF581 ZNF688
Entrez ID		54910	9240
HPRD ID		07257	04926
Ensembl ID		ENSG00000168758	ENSG00000176903
Uniprot IDs		Q9C0C4	Q8ND90
PDB IDs		6N5Z
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Intermediate Filament Organization Ionotropic Glutamate Receptor Binding Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Receptor Localization To Synapse Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Synapse Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Morphogenesis Of An Epithelium Structural Molecule Activity Neuromuscular Junction Protein Localization To Cell Junction Tissue Morphogenesis Kinase Binding Postsynaptic Density Membrane Supramolecular Fiber Organization Epidermis Development Chemical Synaptic Transmission Establishment Or Maintenance Of Cell Polarity Neuron Projection Trans-synaptic Signaling Synaptic Signaling GMP Kinase Activity Adherens Junction GDP Metabolic Process Epithelial Cell Differentiation Juxtaparanode Region Of Axon Cellular Response To Potassium Ion Anatomical Structure Morphogenesis Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Response To Potassium Ion Glutamatergic Synapse Protein Localization To Membrane Cytosol AMPA Glutamate Receptor Complex GMP Metabolic Process Cell-cell Signaling Protein Localization To Postsynaptic Membrane Signaling Protein Localization To Postsynapse Cytoskeleton Organization Cell Communication Establishment Of Skin Barrier Skin Epidermis Development Developmental Process	Protein Binding Nucleus Diacylglycerol-dependent Serine/threonine Kinase Activity PAR Polarity Complex
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