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YWHAZ and PPP1CC
Number of citations of the paper that reports this interaction (PubMedID
15028637
)
0
Data Source:
HPRD
(in vitro, in vivo)
YWHAZ
PPP1CC
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
protein phosphatase 1 catalytic subunit gamma
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Focal Adhesion
Vesicle
Melanosome
Extracellular Exosome
Blood Microparticle
Hippocampal Mossy Fiber To CA3 Synapse
Glutamatergic Synapse
Chromosome, Centromeric Region
Kinetochore
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Microtubule Organizing Center
Cytosol
Cytoskeleton
Focal Adhesion
Nuclear Speck
Midbody
Cleavage Furrow
Protein-containing Complex
Dendritic Spine
PTW/PP1 Phosphatase Complex
Presynapse
Postsynapse
Glutamatergic Synapse
Molecular Function
RNA Binding
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Transmembrane Transporter Binding
Cadherin Binding
Phosphoserine Residue Binding
DNA-binding Transcription Factor Binding
Protein Sequestering Activity
RNA Binding
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Lamin Binding
Protein Phosphatase 1 Binding
Hydrolase Activity
Phosphatase Activity
Protein Kinase Binding
Protein Phosphatase Binding
Protein Domain Specific Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Respiratory System Process
Protein Phosphorylation
Protein Targeting
Lysosome Organization
Signal Transduction
Synaptic Target Recognition
Intracellular Protein Localization
Lung Development
Regulation Of Protein Stability
Cellular Response To Nutrient Levels
Tube Formation
TORC1 Signaling
Cellular Response To Glucose Starvation
Negative Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Negative Regulation Of Innate Immune Response
Establishment Of Golgi Localization
ERK1 And ERK2 Cascade
Regulation Of ERK1 And ERK2 Cascade
Regulation Of Synapse Maturation
Golgi Reassembly
Antibacterial Innate Immune Response
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of TORC1 Signaling
Regulation Of Lysosome Organization
Mitotic Sister Chromatid Segregation
MAPK Cascade
Blastocyst Development
Glycogen Metabolic Process
Protein Dephosphorylation
Spermatogenesis
Neuron Differentiation
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Nucleocytoplasmic Transport
Rhythmic Process
Cell Division
Positive Regulation Of Glial Cell Proliferation
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Deactivation of the beta-catenin transactivating complex
Rap1 signalling
GP1b-IX-V activation signalling
KSRP (KHSRP) binds and destabilizes mRNA
Interleukin-3, Interleukin-5 and GM-CSF signaling
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
NOTCH4 Activation and Transmission of Signal to the Nucleus
Negative regulation of NOTCH4 signaling
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Triglyceride catabolism
Downregulation of TGF-beta receptor signaling
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
RAF activation
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
SHOC2 M1731 mutant abolishes MRAS complex function
Gain-of-function MRAS complexes activate RAF signaling
Maturation of hRSV A proteins
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Drugs
Phenethyl Isothiocyanate
9,10-Deepithio-9,10-Didehydroacanthifolicin
Calyculin A
Motuporin
Diseases
GWAS
Adventurousness (
30643258
)
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Body mass index (
25673413
)
Chronotype (
30696823
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
General risk tolerance (MTAG) (
30643258
)
High light scatter reticulocyte count (
32888494
)
Interleukin-10 levels (
22205395
)
Heart rate (
23583979
)
Interacting Genes
204 interacting genes:
AANAT
ABL1
ADAM22
ADRA2A
ADRA2B
ADRA2C
AKAP13
AKT1
APP
ARHGEF2
ATP5F1A
ATXN1
BAD
BCAR1
BCR
BRAF
BSPRY
CBL
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK16
CDK17
CDKN1B
CEP126
CEP131
CFL1
CGNL1
CLIC4
COP1
CPAP
CRBN
CRTC2
CSF2RB
CSNK1A1
CSNK1D
DFFA
DISC1
EFNB3
EGFR
EIF3A
ENO1
EP300
EPB41L1
EPB41L3
ERBB2
ERBB3
EXO1
FAM13B
FHOD1
FNDC3B
FOXO1
FOXO3
FOXO4
GABARAPL2
GABBR1
GCH1
GP1BA
GP1BB
GP5
GSK3B
HDAC4
HDAC9
HMGN1
HSP90AA1
HSPA1A
HSPA1B
HSPB1
HSPB6
IGF1R
IL9R
ING1
INPP5A
IRAG2
IRS1
IRS2
KANK1
KCNK15
KCNK3
KCNK9
KIAA0232
KIAA0930
KIF1C
KIF5B
KLC2
KLC4
KLF11
KRT18
KSR1
LARP1
LATS2
LCP2
LIMK1
LNX1
MADD
MAP2K5
MAP3K2
MAP3K20
MAP3K3
MAP3K4
MAP3K5
MAPK8
MAPKAPK2
MAPT
MARK2
MARK3
MARK4
MDM4
MEF2C
MINK1
MLF1
MPHOSPH9
MSL2
MST1R
MTNR1A
MYH9
NCAM2
NEDD4L
NFATC2
NFATC4
NR4A1
PAK1
PAK4
PARD3
PARD6A
PARD6B
PCNT
PDC
PFKFB2
PIAS1
PPP1CC
PPP1R14A
PPP1R3D
PRKACA
PRKAR1A
PRKCA
PRKCD
PRKCI
PRKCZ
PRLR
PRMT5
PSMA5
PTPN13
PTPRO
RAF1
RALGPS2
RAP1GAP2
RASAL3
REM1
RGS3
RIN1
RPRD1A
RRAD
SAMSN1
SH3GL1
SIK1
SIK3
SIMC1
SLC8A2
SNAPIN
SNX24
SORBS2
SQSTM1
SSX2IP
STK25
STK38
SYN2
SYNPO
SYNPO2
TAB2
TBC1D7
TBXA2R
TERT
TH
TJP2
TLK2
TNFAIP3
TNS1
TP53
TPD52L1
TPH1
TRA2B
TRIM21
TSC1
TSC2
TUBB
UBC
UCHL5
UCP2
UCP3
USP8
VCP
VIM
WEE1
WNK1
WNK2
WWTR1
XRCC6
YAP1
YWHAE
ZNF839
128 interacting genes:
ABT1
ACAD8
AKAP11
ANKRD42
APIP
APP
ASH2L
AURKA
B4GAT1
BMPR2
BTBD10
C14orf180
C1QA
C9orf50
CEP126
CLMN
CLOCK
CLTC
CNST
COPS5
CSNK1A1
CSNK1E
CSNK2B
CSRNP2
CTSL
CYFIP1
DACT1
DEAF1
DELEC1
DYNLT4
DYRK4
EIF2AK2
ELP4
ENKD1
FBXW11
FTL
FXYD6
GLB1L
GOLGA7
GSTZ1
HCFC1
HDAC6
HMGN1
IFTAP
IL3RA
INSYN1
IRAK1
JAK2
KCTD20
KDM4D
KRCC1
LMTK2
MAP4K4
MAPT
MYO16
NAPEPLD
NEK2
NMT2
NONO
NRBP1
NUAK1
PHACTR4
PHC1
PIAS1
POLR1F
PPP1R11
PPP1R15B
PPP1R16A
PPP1R18
PPP1R2
PPP1R2B
PPP1R2C
PPP1R35
PPP1R3A
PPP1R3C
PPP1R3D
PPP1R7
PPP1R8
PPP1R9A
PPP2R5C
PRR16
RAF1
RB1
RIF1
RNF19B
RORC
RPL7
RPRD2
RRM1
RRP1B
SAXO4
SDR39U1
SFRP1
SGCE
SH3RF2
SHANK3
SMARCB1
SMG6
SPATC1L
SPOCD1
STAM
STARD9
SUMO2
TACC2
TBC1D19
TEFM
TEX36
TLX1
TLX3
TMEM120A
TNS1
TOPBP1
TOR1AIP1
TP53
TP53BP2
TPRN
TRA2A
VCP
VSTM4
WBP11
YLPM1
YWHAZ
ZDBF2
ZFYVE9
ZNF24
ZNF318
ZNF629
ZNF667
Entrez ID
7534
5501
HPRD ID
03183
08911
Ensembl ID
ENSG00000164924
ENSG00000186298
Uniprot IDs
D0PNI1
P63104
P36873
PDB IDs
1IB1
1QJA
1QJB
2C1J
2C1N
2O02
2WH0
3CU8
3NKX
3RDH
4BG6
4FJ3
4HKC
4IHL
4N7G
4N7Y
4N84
4WRQ
4ZDR
5D2D
5D3F
5EWZ
5EXA
5J31
5JM4
5M35
5M36
5M37
5NAS
5ULO
5WXN
5XY9
6EF5
6EJL
6EWW
6F08
6F09
6FN9
6FNA
6FNB
6FNC
6Q0K
6RLZ
6U2H
6XAG
6YMO
6YO8
6YOS
6ZFD
6ZFG
7D8H
7D8P
7D9V
7MFD
7MFE
7MFF
7Q16
7ZIT
8A9G
8AH2
8QDV
8WE2
8WF6
9FUM
9FVL
1IT6
1JK7
1U32
2BCD
2BDX
4UT2
4UT3
5INB
5J28
7SD0
8B5R
Enriched GO Terms of Interacting Partners
?
Cytoplasm
Intracellular Signal Transduction
Protein Kinase Activity
Protein Serine Kinase Activity
Protein Serine/threonine Kinase Activity
Kinase Activity
Regulation Of Cell Communication
Regulation Of Signaling
Protein Phosphorylation
Cytosol
Regulation Of Intracellular Signal Transduction
Phosphorylation
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Signal Transduction
Positive Regulation Of Signal Transduction
ATP Binding
Intracellular Signaling Cassette
Regulation Of Protein Modification Process
Protein Modification Process
Regulation Of Cellular Component Organization
Regulation Of Programmed Cell Death
Nucleotide Binding
Regulation Of Protein Localization
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Apoptotic Process
Positive Regulation Of Protein Metabolic Process
Transferase Activity
Positive Regulation Of Intracellular Signal Transduction
Cellular Response To Stress
Negative Regulation Of Programmed Cell Death
Regulation Of Cell Population Proliferation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Signal Transduction
Cellular Response To Oxygen-containing Compound
Regulation Of Phosphorus Metabolic Process
Regulation Of Multicellular Organismal Process
Protein Kinase Binding
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Protein Localization
Protein Metabolic Process
Regulation Of Cell Cycle
Cell Surface Receptor Signaling Pathway
Response To Stress
Protein-containing Complex
MAPK Cascade
Positive Regulation Of Cellular Component Organization
Protein Phosphatase 1 Binding
Protein Phosphatase Inhibitor Activity
Phosphatase Binding
Protein Phosphatase Regulator Activity
Protein Serine/threonine Kinase Activity
Protein Phosphorylation
Protein Serine/threonine Phosphatase Inhibitor Activity
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Phosphatase Type 1 Complex
Phosphorylation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Viral Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Protein Catabolic Process
Regulation Of Proteolysis
Macromolecule Metabolic Process
Nucleoplasm
Protein Kinase Activity
Positive Regulation Of Proteasomal Protein Catabolic Process
Inclusion Body Assembly
Glycogen Binding
Disordered Domain Specific Binding
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Microtubule Cytoskeleton Organization Involved In Mitosis
Regulation Of Generation Of Precursor Metabolites And Energy
Microglial Cell Activation
Protein Serine Kinase Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Protein Phosphatase Binding
Nucleus
Glycogen Metabolic Process
Leukocyte Activation Involved In Inflammatory Response
Chromatin Remodeling
Actin Binding
Regulation Of Protein Metabolic Process
Regulation Of Primary Metabolic Process
Chromatin Organization
Protein Modification Process
Regulation Of Proteasomal Protein Catabolic Process
PML Body
Type II Interferon-mediated Signaling Pathway
Germ Cell Nucleus
Polysaccharide Metabolic Process
Regulation Of Circadian Rhythm
Energy Reserve Metabolic Process
Epigenetic Regulation Of Gene Expression
DNA Damage Response
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Astrocyte Activation
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Tagcloud (Intersection)
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