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YWHAZ and CDK11B
Number of citations of the paper that reports this interaction (PubMedID
15883043
)
0
Data Source:
BioGRID
(pull down)
YWHAZ
CDK11B
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
cyclin dependent kinase 11B
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Focal Adhesion
Vesicle
Melanosome
Extracellular Exosome
Blood Microparticle
Hippocampal Mossy Fiber To CA3 Synapse
Glutamatergic Synapse
Cyclin-dependent Protein Kinase Holoenzyme Complex
Nucleus
Cytoplasm
Molecular Function
RNA Binding
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Transmembrane Transporter Binding
Cadherin Binding
Phosphoserine Residue Binding
DNA-binding Transcription Factor Binding
Protein Sequestering Activity
Nucleotide Binding
RNA Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Serine Kinase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Respiratory System Process
Protein Phosphorylation
Protein Targeting
Lysosome Organization
Signal Transduction
Synaptic Target Recognition
Intracellular Protein Localization
Lung Development
Regulation Of Protein Stability
Cellular Response To Nutrient Levels
Tube Formation
TORC1 Signaling
Cellular Response To Glucose Starvation
Negative Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Negative Regulation Of Innate Immune Response
Establishment Of Golgi Localization
ERK1 And ERK2 Cascade
Regulation Of ERK1 And ERK2 Cascade
Regulation Of Synapse Maturation
Golgi Reassembly
Antibacterial Innate Immune Response
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of TORC1 Signaling
Regulation Of Lysosome Organization
Mitotic Cell Cycle
Regulation Of Cell Growth
Regulation Of DNA-templated Transcription
Protein Phosphorylation
Apoptotic Process
Regulation Of Apoptotic Process
Regulation Of RNA Splicing
Regulation Of Centrosome Cycle
Regulation Of MRNA Processing
Regulation Of Cell Cycle
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Deactivation of the beta-catenin transactivating complex
Rap1 signalling
GP1b-IX-V activation signalling
KSRP (KHSRP) binds and destabilizes mRNA
Interleukin-3, Interleukin-5 and GM-CSF signaling
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
NOTCH4 Activation and Transmission of Signal to the Nucleus
Negative regulation of NOTCH4 signaling
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
Recruitment of mitotic centrosome proteins and complexes
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Adventurousness (
30643258
)
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Body mass index (
25673413
)
Chronotype (
30696823
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
General risk tolerance (MTAG) (
30643258
)
High light scatter reticulocyte count (
32888494
)
Interleukin-10 levels (
22205395
)
Body mass index (
26426971
)
Interacting Genes
204 interacting genes:
AANAT
ABL1
ADAM22
ADRA2A
ADRA2B
ADRA2C
AKAP13
AKT1
APP
ARHGEF2
ATP5F1A
ATXN1
BAD
BCAR1
BCR
BRAF
BSPRY
CBL
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK16
CDK17
CDKN1B
CEP126
CEP131
CFL1
CGNL1
CLIC4
COP1
CPAP
CRBN
CRTC2
CSF2RB
CSNK1A1
CSNK1D
DFFA
DISC1
EFNB3
EGFR
EIF3A
ENO1
EP300
EPB41L1
EPB41L3
ERBB2
ERBB3
EXO1
FAM13B
FHOD1
FNDC3B
FOXO1
FOXO3
FOXO4
GABARAPL2
GABBR1
GCH1
GP1BA
GP1BB
GP5
GSK3B
HDAC4
HDAC9
HMGN1
HSP90AA1
HSPA1A
HSPA1B
HSPB1
HSPB6
IGF1R
IL9R
ING1
INPP5A
IRAG2
IRS1
IRS2
KANK1
KCNK15
KCNK3
KCNK9
KIAA0232
KIAA0930
KIF1C
KIF5B
KLC2
KLC4
KLF11
KRT18
KSR1
LARP1
LATS2
LCP2
LIMK1
LNX1
MADD
MAP2K5
MAP3K2
MAP3K20
MAP3K3
MAP3K4
MAP3K5
MAPK8
MAPKAPK2
MAPT
MARK2
MARK3
MARK4
MDM4
MEF2C
MINK1
MLF1
MPHOSPH9
MSL2
MST1R
MTNR1A
MYH9
NCAM2
NEDD4L
NFATC2
NFATC4
NR4A1
PAK1
PAK4
PARD3
PARD6A
PARD6B
PCNT
PDC
PFKFB2
PIAS1
PPP1CC
PPP1R14A
PPP1R3D
PRKACA
PRKAR1A
PRKCA
PRKCD
PRKCI
PRKCZ
PRLR
PRMT5
PSMA5
PTPN13
PTPRO
RAF1
RALGPS2
RAP1GAP2
RASAL3
REM1
RGS3
RIN1
RPRD1A
RRAD
SAMSN1
SH3GL1
SIK1
SIK3
SIMC1
SLC8A2
SNAPIN
SNX24
SORBS2
SQSTM1
SSX2IP
STK25
STK38
SYN2
SYNPO
SYNPO2
TAB2
TBC1D7
TBXA2R
TERT
TH
TJP2
TLK2
TNFAIP3
TNS1
TP53
TPD52L1
TPH1
TRA2B
TRIM21
TSC1
TSC2
TUBB
UBC
UCHL5
UCP2
UCP3
USP8
VCP
VIM
WEE1
WNK1
WNK2
WWTR1
XRCC6
YAP1
YWHAE
ZNF839
26 interacting genes:
AP2M1
CASP1
CASP3
CASP8
CCND3
CCNL2
CHEK2
EIF3F
H1-1
KAT7
MSN
PAK1
PDE4B
PIN1
RANBP9
RNF10
RPS27A
TCEA2
TH
TPPP
URM1
YWHAB
YWHAE
YWHAG
YWHAQ
YWHAZ
Entrez ID
7534
984
HPRD ID
03183
08909
Ensembl ID
ENSG00000164924
ENSG00000248333
Uniprot IDs
D0PNI1
P63104
B4DII1
P21127
PDB IDs
1IB1
1QJA
1QJB
2C1J
2C1N
2O02
2WH0
3CU8
3NKX
3RDH
4BG6
4FJ3
4HKC
4IHL
4N7G
4N7Y
4N84
4WRQ
4ZDR
5D2D
5D3F
5EWZ
5EXA
5J31
5JM4
5M35
5M36
5M37
5NAS
5ULO
5WXN
5XY9
6EF5
6EJL
6EWW
6F08
6F09
6FN9
6FNA
6FNB
6FNC
6Q0K
6RLZ
6U2H
6XAG
6YMO
6YO8
6YOS
6ZFD
6ZFG
7D8H
7D8P
7D9V
7MFD
7MFE
7MFF
7Q16
7ZIT
8A9G
8AH2
8QDV
8WE2
8WF6
9FUM
9FVL
7UKZ
Enriched GO Terms of Interacting Partners
?
Cytoplasm
Intracellular Signal Transduction
Protein Kinase Activity
Protein Serine Kinase Activity
Protein Serine/threonine Kinase Activity
Kinase Activity
Regulation Of Cell Communication
Regulation Of Signaling
Protein Phosphorylation
Cytosol
Regulation Of Intracellular Signal Transduction
Phosphorylation
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Signal Transduction
Positive Regulation Of Signal Transduction
ATP Binding
Intracellular Signaling Cassette
Regulation Of Protein Modification Process
Protein Modification Process
Regulation Of Cellular Component Organization
Regulation Of Programmed Cell Death
Nucleotide Binding
Regulation Of Protein Localization
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Apoptotic Process
Positive Regulation Of Protein Metabolic Process
Transferase Activity
Positive Regulation Of Intracellular Signal Transduction
Cellular Response To Stress
Negative Regulation Of Programmed Cell Death
Regulation Of Cell Population Proliferation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Signal Transduction
Cellular Response To Oxygen-containing Compound
Regulation Of Phosphorus Metabolic Process
Regulation Of Multicellular Organismal Process
Protein Kinase Binding
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Protein Localization
Protein Metabolic Process
Regulation Of Cell Cycle
Cell Surface Receptor Signaling Pathway
Response To Stress
Protein-containing Complex
MAPK Cascade
Positive Regulation Of Cellular Component Organization
Phosphoserine Residue Binding
Protein Targeting
Protein Sequestering Activity
Cytosol
Nucleus
Transmembrane Transporter Binding
Focal Adhesion
Regulation Of Protein Localization
Vesicle
Protein Modification Process
Cytoplasm
Protein Domain Specific Binding
Enzyme Binding
Post-translational Protein Modification
Phosphoprotein Binding
Identical Protein Binding
Response To Anesthetic
Regulation Of Primary Metabolic Process
Pyroptotic Inflammatory Response
Regulation Of Macromolecule Metabolic Process
Cysteine-type Peptidase Activity
Death-inducing Signaling Complex
Regulation Of Amyloid Precursor Protein Catabolic Process
Regulation Of Immune System Process
Positive Regulation Of Pyroptotic Inflammatory Response
Ubiquitin Protein Ligase Binding
Regulation Of Protein Localization To Nucleus
Response To Cobalt Ion
Cysteine-type Endopeptidase Activity
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Metabolic Process
Protein Metabolic Process
Regulation Of System Process
Negative Regulation Of Signal Transduction
Interleukin-18-mediated Signaling Pathway
Intracellular Signal Transduction
Protein Tag Activity
Regulation Of Protein Stability
Protein Catabolic Process
Immune System Process
Proteolysis
Death Receptor Binding
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Protein Poly-ADP-ribosylation
Response To Starvation
Positive Regulation Of Myelination
Cellular Response To Stress
Regulation Of Gene Expression
Microtubule Polymerization
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Tagcloud (Intersection)
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