SEMA4B and GIPC1

Number of citations of the paper that reports this interaction (PMID 15978582)
8

Data Source:
HPRD (in vivo, in vitro)

		SEMA4B	GIPC1
Gene Name		sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	GIPC PDZ domain containing family, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Synapse	Cytoplasm Cytosol Brush Border Cell Cortex Synaptic Vesicle Vesicle Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Endocytic Vesicle Dendritic Spine Dendritic Shaft Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity	Actin Binding Receptor Binding Protein Binding Myosin Binding PDZ Domain Binding Protein Homodimerization Activity
	Biological Process	Nervous System Development Cell Differentiation	Protein Targeting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Endothelial Cell Migration Regulation Of Synaptic Plasticity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: DLG4 GIPC1 PLXNB1	31 interactors: ACTN1 ADRB1 CD93 DDIT3 DRD2 DRD3 FZD3 GSK3B IGF1R ITGA5 ITGA6 KIF1B LHCGR LRP1 LRP2 LRP8 MYO6 NRP1 NTRK1 NTRK2 RGS1 RGS19 SDC4 SEMA4B SEMA4C SLC2A1 TGFBR3 TPBG TYRP1 ZFPM1 ZNF408
Entrez ID		10509	10755
HPRD ID		10217	05462
Ensembl ID		ENSG00000185033	ENSG00000123159
Uniprot IDs		J3KNP4	A8K2I7 O14908
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Synaptic Plasticity Locomotion Movement Of Cell Or Subcellular Component Regulation Of Synaptic Transmission Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis Maintenance Of Apical/basal Cell Polarity Axon Guidance Receptor Localization To Synapse Positive Regulation Of Ras GTPase Activity Negative Regulation Of Receptor Internalization Locomotory Exploration Behavior Dendritic Spine Morphogenesis Secretion By Cell Maintenance Of Cell Polarity Negative Regulation Of Osteoblast Proliferation Synaptic Vesicle Maturation Axonogenesis Regulation Of Ras GTPase Activity Regulation Of Signal Transduction Axon Development Vocalization Behavior Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Chemotaxis Ossification Involved In Bone Maturation Dendritic Spine Development Secretion Neuron Projection Morphogenesis Protein Localization To Synapse Regulation Of Signaling Bone Maturation Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Ras Protein Signal Transduction Bone Trabecula Morphogenesis Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Glutamate Secretion Cell Morphogenesis Involved In Differentiation Positive Regulation Of GTPase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Osteoblast Proliferation Cortical Actin Cytoskeleton Organization Regulation Of GTPase Activity Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Neuron Projection Development	Response To External Stimulus Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Positive Regulation Of Phosphorylation Response To Abiotic Stimulus Cell Surface Receptor Signaling Pathway Cell Communication System Development Regulation Of CAMP Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Anatomical Structure Development Positive Regulation Of Metabolic Process Developmental Process Cognition Regulation Of CAMP Metabolic Process Signaling Regulation Of Signal Transduction Signal Transduction Multicellular Organismal Development Movement Of Cell Or Subcellular Component Cell Differentiation Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Learning Or Memory Cell Migration Negative Regulation Of Signal Transduction Activation Of Adenylate Cyclase Activity Anatomical Structure Morphogenesis Regulation Of Cell Development Response To Radiation Tissue Development Cellular Response To Stimulus Regulation Of Synaptic Transmission Cell Motility Regulation Of Apoptotic Process Negative Regulation Of Signaling Positive Regulation Of Adenylate Cyclase Activity Organ Development Response To Stimulus Response To Wounding Positive Regulation Of Cell Development Cell Morphogenesis Involved In Differentiation Response To Light Stimulus Positive Regulation Of Protein Phosphorylation Regulation Of Cell Death Locomotion Regulation Of Cell Differentiation Nervous System Development
Tagcloud ?			adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc2 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2
Tagcloud (Difference) ?			adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc2 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2
Tagcloud (Intersection) ?