Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SEMA4B and DLG4
Number of citations of the paper that reports this interaction (PMID
15978582
)
8
Data Source:
HPRD
(in vitro, in vivo)
SEMA4B
DLG4
Gene Name
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
discs, large homolog 4 (Drosophila)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Synapse
Cytoplasm
Endoplasmic Reticulum
Plasma Membrane
Synaptic Vesicle
Voltage-gated Potassium Channel Complex
Ionotropic Glutamate Receptor Complex
Postsynaptic Density
Basolateral Plasma Membrane
Cell Junction
Endocytic Vesicle Membrane
Cortical Cytoskeleton
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex
Dendrite Cytoplasm
Dendritic Spine
Juxtaparanode Region Of Axon
Cerebellar Mossy Fiber
Neuron Projection Terminus
Neuron Spine
Synapse
Postsynaptic Membrane
Excitatory Synapse
Neuronal Postsynaptic Density
Molecular Function
Receptor Activity
Guanylate Kinase Activity
Protein Binding
Protein C-terminus Binding
Protein Phosphatase Binding
PDZ Domain Binding
Beta-1 Adrenergic Receptor Binding
D1 Dopamine Receptor Binding
P2Y1 Nucleotide Receptor Binding
Protein Complex Binding
Acetylcholine Receptor Binding
Ionotropic Glutamate Receptor Binding
Scaffold Protein Binding
Biological Process
Nervous System Development
Cell Differentiation
Negative Regulation Of Receptor Internalization
Protein Complex Assembly
Signal Transduction
Positive Regulation Of Cytosolic Calcium Ion Concentration
Synaptic Transmission
Nervous System Development
Axon Guidance
Learning
Synaptic Vesicle Maturation
Social Behavior
Protein Localization To Synapse
Locomotory Exploration Behavior
Establishment Of Protein Localization
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Nucleotide Phosphorylation
Regulation Of Long-term Neuronal Synaptic Plasticity
Positive Regulation Of Synaptic Transmission
Neuromuscular Process Controlling Balance
Dendritic Spine Morphogenesis
Vocalization Behavior
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Receptor Localization To Synapse
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Grooming Behavior
Pathways
Axon guidance
L1CAM interactions
Activation of Kainate Receptors upon glutamate binding
CREB phosphorylation through the activation of Ras
Trafficking of AMPA receptors
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
NrCAM interactions
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Activation of Ca-permeable Kainate Receptor
Unblocking of NMDA receptor, glutamate binding and activation
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ionotropic activity of Kainate Receptors
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Liver enzyme levels (alkaline phosphatase) (
22001757
)
Protein-Protein Interactions
3 interactors:
DLG4
GIPC1
PLXNB1
104 interactors:
ACTN2
ADRB1
AKAP5
ARHGAP32
ASIC3
ATP2B2
ATP2B4
BAI1
BEGAIN
CACNG2
CASK
CD46
CIT
CNKSR2
CRIPT
DLG2
DLG3
DLGAP1
DLGAP2
DLGAP3
DLGAP4
DYNLL1
EFNB2
ERBB2
ERBB2IP
ERBB4
EXOC4
FYN
FZD1
FZD2
FZD4
FZD7
GDA
GLS2
GNG13
GRASP
GRIK1
GRIK2
GRIK5
GRIN1
GRIN2A
GRIN2B
GRIN2C
GRIN2D
GRIN3A
GRIN3B
GUCY1A2
HGS
HTR2A
HTR2C
HTT
IL13RA1
KCNA1
KCNA2
KCNA3
KCNA4
KCNA5
KCND2
KCNJ10
KCNJ12
KCNJ2
KCNJ4
KHDRBS1
KIF13B
KIF1B
LIN7A
LIN7B
LPHN1
LRFN1
LRP1
LRP2
LRP8
LRRC1
LYN
MAP1A
MAP3K10
MAPK12
MDM2
NCKIPSD
NDOR1
NLGN1
NLGN2
NLGN3
NLGN4X
NOS1
PCDH10
PRKCA
PTK2B
PTPRG
SCN5A
SEMA4B
SEMA4C
SEMA4F
SEMA4G
SHANK1
SHANK2
SIPA1L1
SPRR2A
SRC
SYNGAP1
TANC1
WNT3A
YES1
ZDHHC17
Entrez ID
10509
1742
HPRD ID
10217
04199
Ensembl ID
ENSG00000185033
ENSG00000132535
Uniprot IDs
J3KNP4
B7Z647
B9EGL1
P78352
PDB IDs
1KEF
3I4W
3K82
3ZRT
Enriched GO Terms of Interacting Partners
?
Regulation Of Synaptic Plasticity
Locomotion
Movement Of Cell Or Subcellular Component
Regulation Of Synaptic Transmission
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Regulation Of Grooming Behavior
Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis
Maintenance Of Apical/basal Cell Polarity
Axon Guidance
Receptor Localization To Synapse
Positive Regulation Of Ras GTPase Activity
Negative Regulation Of Receptor Internalization
Locomotory Exploration Behavior
Dendritic Spine Morphogenesis
Secretion By Cell
Maintenance Of Cell Polarity
Negative Regulation Of Osteoblast Proliferation
Synaptic Vesicle Maturation
Axonogenesis
Regulation Of Ras GTPase Activity
Regulation Of Signal Transduction
Axon Development
Vocalization Behavior
Cell Morphogenesis Involved In Neuron Differentiation
Synaptic Transmission
Chemotaxis
Ossification Involved In Bone Maturation
Dendritic Spine Development
Secretion
Neuron Projection Morphogenesis
Protein Localization To Synapse
Regulation Of Signaling
Bone Maturation
Negative Regulation Of Receptor-mediated Endocytosis
Regulation Of Ras Protein Signal Transduction
Bone Trabecula Morphogenesis
Dendritic Spine Organization
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Glutamate Secretion
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of GTPase Activity
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Osteoblast Proliferation
Cortical Actin Cytoskeleton Organization
Regulation Of GTPase Activity
Exploration Behavior
Postsynaptic Membrane Organization
Establishment Or Maintenance Of Apical/basal Cell Polarity
Neuron Projection Development
Cell-cell Signaling
Synaptic Transmission
Signaling
Cell Communication
Regulation Of Membrane Potential
Regulation Of Ion Transport
Regulation Of Ion Transmembrane Transport
Membrane Depolarization
Nervous System Development
Regulation Of Postsynaptic Membrane Potential
Regulation Of Signaling
Ionotropic Glutamate Receptor Signaling Pathway
Regulation Of Synaptic Transmission
Regulation Of Excitatory Postsynaptic Membrane Potential
Neurological System Process
Neuron-neuron Synaptic Transmission
Glutamate Receptor Signaling Pathway
Signal Transduction
Metal Ion Transport
Synaptic Transmission, Glutamatergic
Neurogenesis
Response To Stimulus
Ion Transport
Generation Of Neurons
Cellular Response To Stimulus
Transport
System Development
Cation Transport
Cell Surface Receptor Signaling Pathway
Single-organism Behavior
Sensory Perception Of Pain
Behavior
Neuron Differentiation
Regulation Of Signal Transduction
Response To Abiotic Stimulus
Ion Transmembrane Transport
Regulation Of Cellular Localization
Anatomical Structure Development
Regulation Of Cellular Process
Membrane Hyperpolarization
Cell Differentiation
Cation Transmembrane Transport
Multicellular Organismal Development
Developmental Process
Regulation Of Phosphorus Metabolic Process
Learning
Response To External Stimulus
Cellular Process
Neuron Development
Positive Regulation Of Signal Transduction
Tagcloud
?
6g1
alleviated
amyloid
ca1
counteract
densities
distant
fibrillar
immunohistochemically
immunotherapy
oligomer
oligomeric
oligomers
plaque
plaques
presynapses
psd95
quantified
reservoirs
sequestering
suffices
synapse
synapses
synapsin
synaptotoxic
tg2576
unchanged
unspecific
vicinity
Tagcloud (Difference)
?
6g1
alleviated
amyloid
ca1
counteract
densities
distant
fibrillar
immunohistochemically
immunotherapy
oligomer
oligomeric
oligomers
plaque
plaques
presynapses
psd95
quantified
reservoirs
sequestering
suffices
synapse
synapses
synapsin
synaptotoxic
tg2576
unchanged
unspecific
vicinity
Tagcloud (Intersection)
?