SEMA4B and CPEB2

Number of citations of the paper that reports this interaction (PubMedID 22157746)
54

Data Source:
BioGRID (two hybrid)

		SEMA4B	CPEB2
Description		semaphorin 4B	cytoplasmic polyadenylation element binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Nucleus Cytoplasm Neuron Projection Synapse
	Molecular Function	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity	MRNA Regulatory Element Binding Translation Repressor Activity Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding Translation Regulator Activity
	Biological Process	Neural Crest Cell Migration Nervous System Development Axon Guidance Cell Differentiation Positive Regulation Of Cell Migration Negative Chemotaxis Semaphorin-plexin Signaling Pathway	Translation Regulation Of Translation Cellular Response To Insulin Stimulus Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 30542056) Frontal fibrosing alopecia ( 30850646) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301)	Cognitive flexibility ( 30134085) Triglyceride levels ( 32203549) Type 2 diabetes ( 33479058)
Interacting Genes		4 interacting genes: CPEB2 DLG4 GIPC1 PLXNB1	26 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A DMRTB1 ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 RBPMS SEMA4B SORBS3 SPARC TFIP11 TUBA1A U2AF1 USP42
Entrez ID		10509	132864
HPRD ID		10217	16744
Ensembl ID		ENSG00000185033	ENSG00000137449
Uniprot IDs		Q9NPR2	A0A5K1VW61 A0A5K1VW71 A0A5K1VW79 A0A5K1VW93 Q7Z5Q1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebellar Mossy Fiber Synaptic Vesicle Juxtaparanode Region Of Axon Synaptic Vesicle Maturation P2Y1 Nucleotide Receptor Binding Regulation Of Synaptic Plasticity Locomotory Exploration Behavior Cell Projection Morphogenesis Positive Regulation Of Signal Transduction Neuron Spine Cellular Response To Potassium Ion Positive Regulation Of Neuron Projection Arborization AMPA Glutamate Receptor Clustering Regulation Of Neuron Projection Arborization Beta-1 Adrenergic Receptor Binding D1 Dopamine Receptor Binding Regulation Of Grooming Behavior NMDA Selective Glutamate Receptor Signaling Pathway Dendritic Spine Neuron Projection Morphogenesis Acetylcholine Receptor Binding Neuron Projection Glutamatergic Synapse Neurotransmitter-gated Ion Channel Clustering Trans-synaptic Signaling Positive Regulation Of Cell Projection Organization Synaptic Signaling Chemical Synaptic Transmission Regulation Of Cell Morphogenesis Neuroligin Family Protein Binding Postsynaptic Membrane Semaphorin Receptor Activity GTPase Activating Protein Binding Negative Regulation Of Osteoblast Proliferation Ossification Involved In Bone Maturation Semaphorin Receptor Complex Cellular Response To Interleukin-7 Regulation Of Melanin Biosynthetic Process Response To Interleukin-7 Positive Regulation Of Melanin Biosynthetic Process Glutamate Secretion GTPase Inhibitor Activity Negative Regulation Of Cytoplasmic Translation Negative Regulation Of Translational Elongation Ribosomal Large Subunit Binding Regulation Of Translational Elongation Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Receptor Internalization MRNA Regulatory Element Binding Translation Repressor Activity Response To Potassium Ion
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