SEMA4B

Description		semaphorin 4B
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Neural Crest Cell Migration Nervous System Development Axon Guidance Cell Differentiation Positive Regulation Of Cell Migration Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 30542056) Frontal fibrosing alopecia ( 30850646) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		4 interacting genes: CPEB2 DLG4 GIPC1 PLXNB1
Entrez ID		10509
HPRD ID		10217
Ensembl ID		ENSG00000185033
Uniprot IDs		Q9NPR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebellar Mossy Fiber Synaptic Vesicle Juxtaparanode Region Of Axon Synaptic Vesicle Maturation P2Y1 Nucleotide Receptor Binding Regulation Of Synaptic Plasticity Locomotory Exploration Behavior Cell Projection Morphogenesis Positive Regulation Of Signal Transduction Neuron Spine Cellular Response To Potassium Ion Positive Regulation Of Neuron Projection Arborization AMPA Glutamate Receptor Clustering Regulation Of Neuron Projection Arborization Beta-1 Adrenergic Receptor Binding D1 Dopamine Receptor Binding Regulation Of Grooming Behavior NMDA Selective Glutamate Receptor Signaling Pathway Dendritic Spine Neuron Projection Morphogenesis Acetylcholine Receptor Binding Neuron Projection Glutamatergic Synapse Neurotransmitter-gated Ion Channel Clustering Trans-synaptic Signaling Positive Regulation Of Cell Projection Organization Synaptic Signaling Chemical Synaptic Transmission Regulation Of Cell Morphogenesis Neuroligin Family Protein Binding Postsynaptic Membrane Semaphorin Receptor Activity GTPase Activating Protein Binding Negative Regulation Of Osteoblast Proliferation Ossification Involved In Bone Maturation Semaphorin Receptor Complex Cellular Response To Interleukin-7 Regulation Of Melanin Biosynthetic Process Response To Interleukin-7 Positive Regulation Of Melanin Biosynthetic Process Glutamate Secretion GTPase Inhibitor Activity Negative Regulation Of Cytoplasmic Translation Negative Regulation Of Translational Elongation Ribosomal Large Subunit Binding Regulation Of Translational Elongation Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Receptor Internalization MRNA Regulatory Element Binding Translation Repressor Activity Response To Potassium Ion
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