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HMG20A and CCNK
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
HMG20A
CCNK
Gene Name
high mobility group 20A
cyclin K
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Molecular Function
DNA Binding
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Protein Heterodimerization Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Protein Kinase Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Chromatin Remodeling
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Negative Regulation Of Neuron Differentiation
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
In Utero Embryonic Development
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Mitotic Nuclear Division
Cell Division
Negative Regulation Of Cell Cycle Arrest
Pathways
Drugs
Diseases
GWAS
Type 2 diabetes (
21490949
22693455
21874001
)
Protein-Protein Interactions
19 interactors:
ADD1
BRAP
CCDC136
CCNK
CFAP53
DTNB
FMNL1
GTF2A1L
HPCAL1
KPNA2
MAGOHB
PTH2R
RBM7
RPP30
RSPH9
SCNM1
SMAD4
SYTL4
TESC
26 interactors:
AES
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
DVL3
EFEMP2
FKBP6
HMG20A
KCNRG
KRTAP4-12
LZTS2
NDC80
NECAB2
PIN1
POLR2A
RBPMS
RFX6
RHOXF2
STX11
TSC22D4
UBC
USHBP1
Entrez ID
10363
8812
HPRD ID
16116
10352
Ensembl ID
ENSG00000140382
Uniprot IDs
Q9NP66
O75909
PDB IDs
2I53
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle Process
Regulation Of Ubiquitin-protein Transferase Activity
Heterocycle Metabolic Process
Regulation Of Cell Cycle Arrest
Cellular Aromatic Compound Metabolic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Wnt Signaling Pathway
Regulation Of Cell Cycle
Cell Cycle
Cellular Nitrogen Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Mitotic Cell Cycle Process
Positive Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
PiRNA Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Mitotic Cell Cycle
Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Viral Transcription
Regulation Of Protein Ubiquitination
Tagcloud
?
affects
associate
bulk
cdk12
cdk13
cdk9
cdks
ctd
elongation
far
flag
hct116
heptad
implementing
numerous
paralog
partner
phosphorylate
preferentially
processing
repeat
reveals
rna
sec
seq
snorna
super
tagged
tefb
Tagcloud (Difference)
?
affects
associate
bulk
cdk12
cdk13
cdk9
cdks
ctd
elongation
far
flag
hct116
heptad
implementing
numerous
paralog
partner
phosphorylate
preferentially
processing
repeat
reveals
rna
sec
seq
snorna
super
tagged
tefb
Tagcloud (Intersection)
?