HMG20A and TRAPPC5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HMG20A	TRAPPC5
Description		high mobility group 20A	trafficking protein particle complex subunit 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex TRAPPI Protein Complex TRAPPII Protein Complex TRAPPIII Protein Complex
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport Golgi Vesicle Transport COPII Vesicle Coating Vesicle Tethering
Pathways			COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Fasting glucose ( 34059833) Femur bone mineral density x serum urate levels interaction ( 34046847) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 21874001 22693455 22885922 24509480 28869590 30054458 30297969 30718926 32499647)
Interacting Genes		59 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNB DYRK1A FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM11 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	5 interacting genes: A2M CCNDBP1 HMG20A TRAPPC2B TRAPPC3L
Entrez ID		10363	126003
HPRD ID		16116	15547
Ensembl ID		ENSG00000140382	ENSG00000181029
Uniprot IDs		B4DMG1 Q9NP66	Q8IUR0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	TRAPP Complex Negative Regulation Of Complement Activation, Lectin Pathway Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Interleukin-8 Binding Tumor Necrosis Factor Binding Interleukin-1 Binding Negative Regulation Of Complement Activation Negative Regulation Of Protein Sumoylation TRAPPII Protein Complex Golgi Vesicle Transport TRAPPIII Protein Complex Cis-Golgi Network Membrane
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