HMG20A and FMNL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HMG20A	FMNL1
Gene Name		high mobility group 20A	formin-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol Plasma Membrane Cell Cortex Membrane Bleb Phagocytic Vesicle Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity	Molecular_function Protein Binding Profilin Binding GTPase Activating Protein Binding Rac GTPase Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Differentiation	Substrate-dependent Cell Migration Regulation Of Cell Shape Cortical Actin Cytoskeleton Organization Actin Filament Severing
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 21490949 22693455 21874001)
Protein-Protein Interactions		19 interactors: ADD1 BRAP CCDC136 CCNK CFAP53 DTNB FMNL1 GTF2A1L HPCAL1 KPNA2 MAGOHB PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC	9 interactors: APP GAS7 HMG20A PFN1 PFN2 PRPF40A RAC1 TCERG1 XRCC6
Entrez ID		10363	752
HPRD ID		16116	06876
Ensembl ID		ENSG00000140382	ENSG00000184922
Uniprot IDs		Q9NP66	O95466
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Ruffle Assembly Organelle Organization Cytoskeleton Organization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Hyperosmotic Response Platelet Activation Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Nervous System Development Positive Regulation Of ATPase Activity Actin Filament-based Process Regulation Of ATPase Activity Actin Filament Polymerization Generation Of Neurons Neurogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Development Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Transcription From RNA Polymerase II Promoter Platelet Degranulation Regulation Of Cellular Component Organization Negative Regulation Of Actin Filament Polymerization Regulation Of Actin Filament-based Process Positive Regulation Of Organelle Organization Blood Coagulation Actin Polymerization Or Depolymerization Hemostasis Negative Regulation Of Protein Polymerization Response To Osmotic Stress Regulation Of Cell Morphogenesis Regulation Of Metabolic Process Regulation Of Cell Projection Organization Protein Polymerization Regulation Of Cytoskeleton Organization Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Synaptic Growth At Neuromuscular Junction Regulation Of Body Fluid Levels
Tagcloud ?			actin biochemical cathepsin cation content depletion dispersal distinctly dramatic enlargement formin formins fragmentation golgi ill importantly integrity isoform lysosomal lysosomes maintain maintenance mannose member missorting nucleators phosphate relate
Tagcloud (Difference) ?			actin biochemical cathepsin cation content depletion dispersal distinctly dramatic enlargement formin formins fragmentation golgi ill importantly integrity isoform lysosomal lysosomes maintain maintenance mannose member missorting nucleators phosphate relate
Tagcloud (Intersection) ?