HMG20A and GTF2A1L

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HMG20A	GTF2A1L
Gene Name		high mobility group 20A	general transcription factor IIA, 1-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity	DNA Binding Transcription Coactivator Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Differentiation	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cognition
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 21490949 22693455 21874001)	Polycystic ovary syndrome ( 21151128)
Protein-Protein Interactions		19 interactors: ADD1 BRAP CCDC136 CCNK CFAP53 DTNB FMNL1 GTF2A1L HPCAL1 KPNA2 MAGOHB PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC	25 interactors: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3
Entrez ID		10363	11036
HPRD ID		16116	05640
Ensembl ID		ENSG00000140382	ENSG00000242441
Uniprot IDs		Q9NP66	Q9UNN4
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Multicellular Organismal Development System Development Anatomical Structure Development Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Embryo Development Cell Differentiation Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Organ Development Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Organ Morphogenesis Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Generation Of Neurons Positive Regulation Of Cellular Metabolic Process Neurogenesis Cerebral Cortex Regionalization Positive Regulation Of Metabolic Process Neuron Differentiation Telencephalon Regionalization Pattern Specification Process Regulation Of Cell Differentiation Embryonic Organ Development Anterior/posterior Pattern Specification
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