HMG20A and GTF2A1L

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		HMG20A	GTF2A1L
Description		high mobility group 20A	general transcription factor IIA subunit 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Male Germ Cell Nucleus Nucleus Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	DNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription Cognition
Pathways
Drugs
Diseases
GWAS		Fasting glucose ( 34059833) Femur bone mineral density x serum urate levels interaction ( 34046847) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 21874001 22693455 22885922 24509480 28869590 30054458 30297969 30718926 32499647)	Adult body size ( 32376654) Hepcidin/ferritin ratio ( 27846281) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Joint mobility (Beighton score) ( 27182965) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 21151128)
Interacting Genes		59 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNB DYRK1A FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM11 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	25 interacting genes: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3
Entrez ID		10363	11036
HPRD ID		16116	05640
Ensembl ID		ENSG00000140382	ENSG00000242441
Uniprot IDs		B4DMG1 Q9NP66	Q9UNN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Regulation Of RNA Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nucleus Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Morphogenesis Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Animal Organ Development Developmental Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Protein Kinase CK2 Complex System Development Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Transcription Factor TFIIA Complex DNA-templated Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cerebral Cortex Regionalization Regionalization RNA Polymerase II General Transcription Initiation Factor Binding Central Nervous System Development Nucleoplasm Anterior/posterior Pattern Specification RNA Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Neuron Differentiation Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Embryonic Skeletal System Morphogenesis
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