HMG20A and MAGOHB

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		HMG20A	MAGOHB
Gene Name		high mobility group 20A	mago-nashi homolog B (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity	Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Differentiation	MRNA Processing RNA Splicing MRNA Transport
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 21490949 22693455 21874001)
Protein-Protein Interactions		19 interactors: ADD1 BRAP CCDC136 CCNK CFAP53 DTNB FMNL1 GTF2A1L HPCAL1 KPNA2 MAGOHB PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC	20 interactors: AES AMOTL2 CALCOCO2 CCDC102B GOLGA2 HMG20A IKZF3 KRT40 MID2 RBM8A RBMX REL RUNDC3A TCF4 TERF2 TERF2IP TRIM42 YWHAG ZNF250 ZNF398
Entrez ID		10363	55110
HPRD ID		16116	08544
Ensembl ID		ENSG00000140382
Uniprot IDs		Q9NP66	F5H6P7 Q96A72
PDB IDs
Enriched GO Terms of Interacting Partners?			Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Protection From Non-homologous End Joining At Telomere Negative Regulation Of Cellular Metabolic Process Telomere Capping Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Protein Localization To Chromosome, Telomeric Region RNA Metabolic Process Regulation Of Metabolic Process Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Gene Expression Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Telomere Maintenance Biosynthetic Process Regulation Of Gene Expression RNA-dependent DNA Replication Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Binding Regulation Of Transcription, DNA-templated Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Gene Expression Protein Localization To Chromosome Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Regulation Of RNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Nitrogen Compound Metabolic Process Protein Localization To Organelle Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Protein Binding Regulation Of Binding Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of RNA Biosynthetic Process Wnt Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Response To Cytokine Telomere Maintenance Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
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