NPM2 and PLEKHF2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NPM2	PLEKHF2
Gene Name		nucleophosmin/nucleoplasmin 2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Chromatin Nuclear Chromatin Nucleus	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Nucleic Acid Binding Chromatin Binding Enzyme Binding Histone Binding	Protein Binding Metal Ion Binding
	Biological Process	Chromatin Remodeling Regulation Of Exit From Mitosis Single Fertilization Embryo Development Oocyte Differentiation Positive Regulation Of Catalytic Activity Positive Regulation Of DNA Replication Positive Regulation Of Meiotic Nuclear Division Protein Homooligomerization	Protein Transport
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Radiation response ( 20923822)
Protein-Protein Interactions		5 interactors: NPM1 NPM3 PLEKHF2 SDCBP2 SRPK2	52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398
Entrez ID		10361	79666
HPRD ID		12160	15147
Ensembl ID		ENSG00000158806	ENSG00000175895
Uniprot IDs		Q6NVH6 Q86SE8	Q9H8W4
PDB IDs		3T30
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Complex Biogenesis Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Nuclear Speck Organization Ribonucleoprotein Complex Assembly Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity Ribosome Biogenesis Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Regulation Of Centriole Replication Negative Regulation Of Centrosome Duplication	Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		autoantigenic chaperones dramatic egg embryogenesis evolutionarily evolutionary evolved fertilization genuine h2a h2b histones monophyletic nasp npm3 nucleoplasmin paternal plethora ptms recurrently reviews revolves somatic sperm storage takes taxa	abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Difference) ?		autoantigenic chaperones dramatic egg embryogenesis evolutionarily evolutionary evolved fertilization genuine h2a h2b histones monophyletic nasp npm3 nucleoplasmin paternal plethora ptms recurrently reviews revolves somatic sperm storage takes taxa	abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Intersection) ?