PCGF3 and DZIP3

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		PCGF3	DZIP3
Gene Name		polycomb group ring finger 3	DAZ interacting zinc finger protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Phosphatase Binding Polyubiquitin Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Polyubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Hemostatic factors and hematological phenotypes ( 22443383)
Protein-Protein Interactions		12 interactors: BCOR BCORL1 BMI1 CBX6 CBX7 CBX8 DZIP3 PHC2 RING1 RNF2 TRIM9 UBE2C	42 interactors: AKTIP AP1M1 ARHGAP32 ATXN1 BIRC2 BIRC3 CEP63 DAZ1 GTF2H2C_2 HNRNPF HNRNPUL1 HOTAIR NCOR1 PCGF3 RAD18 RBM4B RNF38 TOLLIP TRIM21 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765
Entrez ID		10336	9666
HPRD ID		11515	10562
Ensembl ID		ENSG00000185619	ENSG00000198919
Uniprot IDs		B3KWT8 Q3KNV8	Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Protein Ubiquitination Chromatin Modification Protein Modification By Small Protein Conjugation Chromatin Organization Chromosome Organization Histone H2A Monoubiquitination Histone H2A Ubiquitination Histone Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Protein Monoubiquitination Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Organelle Organization Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Cellular Protein Modification Process Gene Expression Pattern Specification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Anterior/posterior Pattern Specification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone H3-K36 Methylation Heterocycle Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Ligase Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Free Ubiquitin Chain Polymerization Negative Regulation Of Tooth Mineralization Negative Regulation Of SNARE Complex Assembly	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Metabolic Process Activation Of Innate Immune Response Cellular Metabolic Process Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Protein Monoubiquitination Proteolysis Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Protein Ubiquitination DNA Repair Regulation Of Metabolic Process Innate Immune Response Immune Response-regulating Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Stress Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Postreplication Repair Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Process
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