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PCGF3 and BMI1
Number of citations of the paper that reports this interaction (PMID
22493164
)
2
Data Source:
BioGRID
(two hybrid)
PCGF3
BMI1
Gene Name
polycomb group ring finger 3
BMI1 proto-oncogene, polycomb ring finger
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
PcG Protein Complex
Ubiquitin Ligase Complex
Heterochromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
RING-like Zinc Finger Domain Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
In Utero Embryonic Development
DNA Methylation
Transcription, DNA-templated
Humoral Immune Response
Segment Specification
Brain Development
Regulation Of Gene Expression
Histone Acetylation
Histone Ubiquitination
Rostrocaudal Neural Tube Patterning
Hemopoiesis
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Immature T Cell Proliferation In Thymus
Somatic Stem Cell Division
Positive Regulation Of Fibroblast Proliferation
Embryonic Skeletal System Morphogenesis
Positive Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Oxidative Stress Induced Senescence
Cellular Senescence
Drugs
Diseases
GWAS
Hemostatic factors and hematological phenotypes (
22443383
)
Protein-Protein Interactions
12 interactors:
BCOR
BCORL1
BMI1
CBX6
CBX7
CBX8
DZIP3
PHC2
RING1
RNF2
TRIM9
UBE2C
35 interactors:
CBX6
CBX7
CBX8
CSNK2B
E2F6
FOXS1
H2AFX
HIST2H2AA3
HIST2H2AC
HIST3H3
IMMT
KAT5
KIAA1377
KMT2A
LRIF1
MAPK14
NDEL1
PCGF3
PCGF6
PHC1
PHC2
PTN
RING1
RNF114
RNF2
RRM1
SOCS2
TRIM27
TUSC3
UBE2D3
UBE2I
USP11
USP7
VPS11
ZBTB16
Entrez ID
10336
648
HPRD ID
11515
01277
Ensembl ID
ENSG00000185619
ENSG00000168283
Uniprot IDs
B3KWT8
Q3KNV8
P35226
PDB IDs
2H0D
3RPG
Enriched GO Terms of Interacting Partners
?
Histone Ubiquitination
Protein Ubiquitination
Chromatin Modification
Protein Modification By Small Protein Conjugation
Chromatin Organization
Chromosome Organization
Histone H2A Monoubiquitination
Histone H2A Ubiquitination
Histone Monoubiquitination
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Histone Modification
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Protein Monoubiquitination
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Organelle Organization
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Cellular Protein Modification Process
Gene Expression
Pattern Specification Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Anterior/posterior Pattern Specification
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Protein Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Histone H3-K36 Methylation
Heterocycle Metabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Metabolic Process
Positive Regulation Of Ligase Activity
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Chromosome Organization
Free Ubiquitin Chain Polymerization
Negative Regulation Of Tooth Mineralization
Negative Regulation Of SNARE Complex Assembly
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Protein Modification By Small Protein Conjugation
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Transcription, DNA-templated
Chromatin Organization
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Chromosome Organization
Chromatin Modification
Histone Ubiquitination
Cellular Macromolecule Biosynthetic Process
Cellular Protein Modification Process
Negative Regulation Of Cellular Metabolic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Histone Modification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Organelle Organization
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Regulation Of Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Protein Monoubiquitination
Proteasomal Protein Catabolic Process
Biosynthetic Process
Cellular Protein Metabolic Process
Regulation Of Gene Expression
Response To Ionizing Radiation
Mitotic Cell Cycle
Cell Cycle
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A Ubiquitination
Protein Metabolic Process
Negative Regulation Of Interleukin-2 Production
Histone Monoubiquitination
Tagcloud
?
activators
coimmunoprecipitate
colocalize
combs
drosophila
eed
enhancer
enx1
esc
example
extra
ezh2
homolog
homology
hpc2
hybrid
interacts
melanogaster
osteosarcoma
pcg
polycomb
progeny
repressors
screen
trithorax
trxg
unlike
z
zeste
Tagcloud (Difference)
?
activators
coimmunoprecipitate
colocalize
combs
drosophila
eed
enhancer
enx1
esc
example
extra
ezh2
homolog
homology
hpc2
hybrid
interacts
melanogaster
osteosarcoma
pcg
polycomb
progeny
repressors
screen
trithorax
trxg
unlike
z
zeste
Tagcloud (Intersection)
?