PCGF3

Description		polycomb group ring finger 3
Image		No pdb structure
GO Annotations	Cellular Component	X Chromosome Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Histone H2AK119 Ubiquitin Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Random Inactivation Of X Chromosome
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) General cognitive ability ( 29844566) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemostatic factors and hematological phenotypes ( 22443383) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Monocyte percentage of white cells ( 27863252 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Schizophrenia ( 33169155) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Type 2 diabetes ( 30297969 32499647) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 27863252 32888494)
Interacting Genes		11 interacting genes: BMI1 DZIP3 HNRNPK PHC1 PHC2 RING1 TRIM55 TRIM63 TRIM9 UBE2C UBE2D3
Entrez ID		10336
HPRD ID		11515
Ensembl ID		ENSG00000185619
Uniprot IDs		B3KQ06 B3KWT8 B4DTN5 Q3KNV8
PDB IDs
Enriched GO Terms of Interacting Partners?		PRC1 Complex Ubiquitin Protein Ligase Activity PcG Protein Complex Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Zinc Ion Binding Sex Chromatin Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin-protein Transferase Activator Activity Ubiquitin-protein Transferase Activity Protein Modification Process Protein Polyubiquitination Transferase Activity Positive Regulation Of Ubiquitin-protein Transferase Activity Protein K48-linked Ubiquitination Ubiquitin Ligase Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Chromatin Binding Ubiquitin Conjugating Enzyme Activity Protein K11-linked Ubiquitination Metal Ion Binding Heterochromatin Negative Regulation Of Metabolic Process Chromatin Remodeling Protein Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Interleukin-1 Regulation Of Adaxial/abaxial Pattern Formation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Negative Regulation Of Biosynthetic Process Nuclear Body Chromatin Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process RING-like Zinc Finger Domain Binding Rostrocaudal Neural Tube Patterning Positive Regulation Of Protein Ubiquitination Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Exit From Mitosis Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Post-translational Protein Modification Regulation Of Primary Metabolic Process Nucleus Response To Glucocorticoid Proteasomal Protein Catabolic Process
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