PCGF3 and TRIM9

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		PCGF3	TRIM9
Gene Name		polycomb group ring finger 3	tripartite motif containing 9
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex	Cytoplasm Cytoskeleton Synaptic Vesicle Cell Junction Dendrite
	Molecular Function	Protein Binding Zinc Ion Binding	SNARE Binding Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Hemostatic factors and hematological phenotypes ( 22443383)
Protein-Protein Interactions		12 interactors: BCOR BCORL1 BMI1 CBX6 CBX7 CBX8 DZIP3 PHC2 RING1 RNF2 TRIM9 UBE2C	28 interactors: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 VASP
Entrez ID		10336	114088
HPRD ID		11515	05947
Ensembl ID		ENSG00000185619	ENSG00000100505
Uniprot IDs		B3KWT8 Q3KNV8	Q9C026
PDB IDs			2DB8
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Protein Ubiquitination Chromatin Modification Protein Modification By Small Protein Conjugation Chromatin Organization Chromosome Organization Histone H2A Monoubiquitination Histone H2A Ubiquitination Histone Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Protein Monoubiquitination Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Organelle Organization Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Cellular Protein Modification Process Gene Expression Pattern Specification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Anterior/posterior Pattern Specification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone H3-K36 Methylation Heterocycle Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Ligase Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Free Ubiquitin Chain Polymerization Negative Regulation Of Tooth Mineralization Negative Regulation Of SNARE Complex Assembly	Protein Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Organelle Organization Regulation Of Protein Stability Cellular Protein Metabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Viral Transcription Protein Complex Assembly Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Release From Host Cell Regulation Of Circadian Rhythm Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Actin Filament Polymerization Cellular Macromolecule Catabolic Process Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Viral Transcription Positive Regulation Of Proteolysis Regulation Of Viral Release From Host Cell Cellular Protein Catabolic Process Positive Regulation Of Protein Polymerization G2/M Transition Of Mitotic Cell Cycle Protein Destabilization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Catabolic Process Anterograde Axon Cargo Transport Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Viral Process Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Positive Regulation Of Organelle Organization Circadian Rhythm Regulation Of Actin Filament Polymerization Organelle Localization Mitotic Cell Cycle Cellular Response To UV-C Cellular Response To Vitamin B1 Posttranscriptional Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Cytoskeleton Organization Establishment Of Vesicle Localization
Tagcloud ?			alteration alterations arf cadps2 frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional tumors
Tagcloud (Difference) ?			alteration alterations arf cadps2 frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional tumors
Tagcloud (Intersection) ?