RASGRP2 and FAM118B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		RASGRP2	FAM118B
Description		RAS guanyl releasing protein 2	family with sequence similarity 118 member B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Ruffle Membrane Cell Projection Neuron Projection Synapse	Nucleus Cajal Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Zinc Ion Binding Lipid Binding Diacylglycerol Binding GTPase Regulator Activity Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cell Growth Signal Transduction Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction Positive Regulation Of GTPase Activity Cellular Response To Calcium Ion
Pathways		Effects of PIP2 hydrolysis FCERI mediated NF-kB activation Integrin signaling Rap1 signalling
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Interacting Genes		9 interacting genes: APP CEBPA DAPK1 DISP3 FAM118B KRAS NRAS RAP1A SNCA	29 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF PDCD10 PIAS2 QARS1 RAD54L2 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746
Entrez ID		10235	79607
HPRD ID		09278	07952
Ensembl ID		ENSG00000068831	ENSG00000197798
Uniprot IDs		B3KV60 Q7LDG7	J3KP39 Q9BPY3
PDB IDs		2MA2 6AXF
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity GDP Binding G Protein Activity Protein-containing Complex Binding Liver Development GTP Binding Intracellular Signaling Cassette Regulation Of Presynapse Organization Intracellular Signal Transduction Positive Regulation Of Inflammatory Response Modulation Of Chemical Synaptic Transmission Positive Regulation Of Endocytosis Regulation Of Presynapse Assembly Regulation Of Neurotransmitter Uptake Cellular Response To Metal Ion Cellular Response To Copper Ion Identical Protein Binding Amyloid Fibril Formation Positive Regulation Of Catabolic Process Regulation Of Synaptic Plasticity Response To Peptide Response To Cytokine Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Response To Copper Ion Cell Surface Receptor Signaling Pathway Negative Regulation Of Exocytosis Presynapse Cellular Response To Nerve Growth Factor Stimulus Homeostatic Process Response To Nerve Growth Factor Regulation Of Neuron Apoptotic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Regulation Of Cell Junction Assembly Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Cognition Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Macrophage Activation Response To Growth Factor Amylin Binding Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning	Protein Sumoylation PML Body Organization
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