Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
FAM118B and GNB2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
FAM118B
GNB2
Gene Name
family with sequence similarity 118, member B
guanine nucleotide binding protein (G protein), beta polypeptide 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cajal Body
Extracellular Space
Lysosomal Membrane
Plasma Membrane
Focal Adhesion
Membrane
Vesicle
Protein Complex
Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
GTPase Activity
Signal Transducer Activity
Calcium Channel Regulator Activity
Protein Binding
Protein Complex Binding
GTPase Binding
Biological Process
Energy Reserve Metabolic Process
G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Small Molecule Metabolic Process
Cellular Response To Glucagon Stimulus
Pathways
Signaling by GPCR
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Glucagon-type ligand receptors
G beta:gamma signalling through PLC beta
Signaling by Wnt
Metabolic disorders of biological oxidation enzymes
G protein gated Potassium channels
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
Glucagon signaling in metabolic regulation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Inwardly rectifying K+ channels
G-protein beta:gamma signalling
Opioid Signalling
Activation of Kainate Receptors upon glutamate binding
Aquaporin-mediated transport
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (q) signalling events
GPCR downstream signaling
Platelet homeostasis
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signal amplification
Potassium Channels
G beta:gamma signalling through PI3Kgamma
G alpha (12/13) signalling events
Class B/2 (Secretin family receptors)
Prostacyclin signalling through prostacyclin receptor
GABA B receptor activation
GABA receptor activation
Activation of G protein gated Potassium channels
Vasopressin regulates renal water homeostasis via Aquaporins
Regulation of insulin secretion
GPCR ligand binding
beta-catenin independent WNT signaling
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Ca2+ pathway
G-protein activation
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
BAG5
CEP70
CTSB
FAM118A
FAM20C
GNB2
ING5
ITFG1
KIAA1377
MCM3AP
MED31
NGEF
QARS
RASGRP2
RBM48
SDCBP
SEMA5B
SETDB1
SHC1
SPRED1
SUMO1
SUMO1P1
TMSB4X
VIM
ZNF235
ZNF746
31 interactors:
ANXA7
ATXN10
CAPNS1
CDKN1A
CSNK1A1
FAM118B
FANCA
GADD45A
GNAI1
GNAI2
GNAI3
GNG10
GNG12
GNG13
GNG3
GNG4
GNG5
GNG7
GNGT1
GRB7
GSK3B
ID3
NR3C1
PCBP1
PDHB
RAF1
RASD2
RCC1
STAT5A
TGFBR1
TSC22D1
Entrez ID
79607
2783
HPRD ID
07952
11820
Ensembl ID
ENSG00000197798
ENSG00000172354
Uniprot IDs
J3KP39
Q9BPY3
P62879
Q6FHM2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Developmental Process
Anatomical Structure Development
Regulation Of Signal Transduction
Platelet Activation
Regulation Of Signaling
Glutaminyl-tRNA Aminoacylation
Osteoclast Maturation
Ras Protein Signal Transduction
Organelle Organization
Regulation Of Cellular Component Organization
Multicellular Organismal Development
Peptidyl-lysine Modification
Prolyl-tRNA Aminoacylation
Regulation Of Cellular Process
Small GTPase Mediated Signal Transduction
Actin Filament-based Process
Negative Regulation Of Dendritic Spine Morphogenesis
Cytoskeleton Organization
Ephrin Receptor Signaling Pathway
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Glutamyl-tRNA Aminoacylation
PML Body Organization
Negative Regulation Of Protein Refolding
Odontoblast Differentiation
Regulation Of Intracellular Signal Transduction
Cellular Response To Glucagon Stimulus
Response To Glucagon
Synaptic Transmission
Energy Reserve Metabolic Process
Energy Derivation By Oxidation Of Organic Compounds
Cellular Response To Peptide Hormone Stimulus
Response To Peptide Hormone
Cellular Response To Peptide
Response To Peptide
Cell-cell Signaling
Response To Hormone
Cellular Response To Hormone Stimulus
Generation Of Precursor Metabolites And Energy
Cell Surface Receptor Signaling Pathway
Response To Organonitrogen Compound
Cellular Response To Organonitrogen Compound
Signal Transduction
Response To Organic Substance
G-protein Coupled Receptor Signaling Pathway
Signaling
Cellular Response To Organic Substance
Cell Communication
Cellular Response To Stimulus
Response To Stimulus
Regulation Of Cellular Process
Regulation Of Adenylate Cyclase Activity
Regulation Of Cyclase Activity
Regulation Of Signal Transduction
Cell Cycle
Regulation Of CAMP Biosynthetic Process
Regulation Of Body Fluid Levels
Regulation Of Signaling
Positive Regulation Of Programmed Cell Death
Regulation Of Phosphorus Metabolic Process
Regulation Of CAMP Metabolic Process
Positive Regulation Of Cell Death
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Metabolic Process
Hemostasis
Positive Regulation Of Signal Transduction
Response To Wounding
Positive Regulation Of Protein Kinase Activity
Activation Of Protein Kinase Activity
Response To Stress
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Regulation Of Kinase Activity
Regulation Of Apoptotic Process
Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
abl
alterations
bcr
bez235
braf
canonical
cdkn2a
clustered
coexpression
confer
dimer
disrupt
effectors
encoding
galpha
gbeta
gbetagamma
gnb1
i80
interface
k57
neoplasms
oncogenic
partly
substitution
subunits
targetable
v600k
variants
Tagcloud (Difference)
?
abl
alterations
bcr
bez235
braf
canonical
cdkn2a
clustered
coexpression
confer
dimer
disrupt
effectors
encoding
galpha
gbeta
gbetagamma
gnb1
i80
interface
k57
neoplasms
oncogenic
partly
substitution
subunits
targetable
v600k
variants
Tagcloud (Intersection)
?