FAM118B and TMSB4X

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		FAM118B	TMSB4X
Name		family with sequence similarity 118 member B	thymosin beta 4 X-linked
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cajal Body	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Actin Binding Actin Monomer Binding Actin Monomer Sequestering Activity Protein Binding Enzyme Binding Protein Sequestering Activity
	Biological Process	None	Actin Filament Organization Regulation Of Cell Migration Negative Regulation Of Actin Filament Polymerization Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Inflammatory Response Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process
Pathways		None	Platelet degranulation
GWAS		No GWAS studies recorded	Asthma ( 30929738 ) Asthma (childhood onset) ( 30929738 )
Interacting Genes		29 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF PDCD10 PIAS2 QARS1 RAD54L2 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746	38 interacting genes: ACTA1 ACTA2 ACTB ACTG1 AKAP8L ALAS1 ANXA7 APLP1 CDKN1A COG6 FAM118B FHL3 GOLGA6L9 GRB7 HSF2BP IGSF21 ILK KRT13 KRT15 KRT31 KRT34 KRT36 KRT40 KRTAP8-1 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6 UHMK1
Entrez ID		79607	7114
HPRD ID		07952	02153
Ensembl ID		ENSG00000197798	ENSG00000205542
Uniprot IDs		J3KP39 Q9BPY3	A2VCK8 P62328 Q0P5T0
PDB IDs		Not available	3TU5 4PL7 4PL8
GO Terms Enriched among Interactors		Protein Sumoylation PML Body Organization	Morphogenesis Of An Epithelium Structural Constituent Of Skin Epidermis Tissue Morphogenesis Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Epithelial Cell Differentiation Structural Constituent Of Cytoskeleton Cytosol Structural Molecule Activity Focal Adhesion Supramolecular Fiber Organization Regulation Of Transepithelial Transport Stress Fiber Cytoskeleton Organization Mesenchyme Migration Dense Body Protein Kinase Binding Identical Protein Binding Developmental Process Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Platelet Aggregation Organelle Organization Anatomical Structure Morphogenesis Epidermis Development Actin Cytoskeleton Homotypic Cell-cell Adhesion Postsynaptic Actin Cytoskeleton Organization Cellular Response To Catecholamine Stimulus Lamellipodium Protein Localization To Cell-cell Junction Calyx Of Held Response To Catecholamine Actin Filament Postsynaptic Cytoskeleton Organization Protein Binding Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Hepatic Stellate Cell Contraction Apical Junction Complex NuA4 Histone Acetyltransferase Complex Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Synaptic Vesicle Recycling Basal Body Patch Alpha-2B Adrenergic Receptor Binding Peptide Dopaminyltransferase Activity