FAM118B and SEMA5B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FAM118B	SEMA5B
Gene Name		family with sequence similarity 118, member B	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cajal Body	Integral Component Of Membrane
	Molecular Function		Receptor Activity
	Biological Process		Nervous System Development Cell Differentiation
Pathways			Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS			Esophageal cancer ( 21642993)
Protein-Protein Interactions		26 interactors: BAG5 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 KIAA1377 MCM3AP MED31 NGEF QARS RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746	8 interactors: ANXA7 C11orf58 FAM118B MRPL44 NUDT21 SMN1 SPRY2 TK1
Entrez ID		79607	54437
HPRD ID		07952	15322
Ensembl ID		ENSG00000197798	ENSG00000082684
Uniprot IDs		J3KP39 Q9BPY3	B7Z2B3 Q9P283
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Developmental Process Anatomical Structure Development Regulation Of Signal Transduction Platelet Activation Regulation Of Signaling Glutaminyl-tRNA Aminoacylation Osteoclast Maturation Ras Protein Signal Transduction Organelle Organization Regulation Of Cellular Component Organization Multicellular Organismal Development Peptidyl-lysine Modification Prolyl-tRNA Aminoacylation Regulation Of Cellular Process Small GTPase Mediated Signal Transduction Actin Filament-based Process Negative Regulation Of Dendritic Spine Morphogenesis Cytoskeleton Organization Ephrin Receptor Signaling Pathway Positive Regulation Of Extracellular Vesicular Exosome Assembly Glutamyl-tRNA Aminoacylation PML Body Organization Negative Regulation Of Protein Refolding Odontoblast Differentiation Regulation Of Intracellular Signal Transduction	Fetal Process Involved In Parturition Protein Tetramerization RNA Processing Skeletal Muscle Cell Proliferation Response To Cortisol Thymidine Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Deoxyribonucleoside Monophosphate Biosynthetic Process Lung Growth Regulation Of Neurotrophin TRK Receptor Signaling Pathway Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Bud Elongation Involved In Lung Branching Response To Metal Ion Cellular Water Homeostasis RNA Splicing
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