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FEM1B and RAD9A
Number of citations of the paper that reports this interaction (PMID
19330022
)
1
Data Source:
BioGRID
(pull down)
FEM1B
RAD9A
Gene Name
fem-1 homolog b (C. elegans)
RAD9 homolog A (S. pombe)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Checkpoint Clamp Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Death Receptor Binding
Protein Binding
Protein Binding
3'-5' Exonuclease Activity
Exodeoxyribonuclease III Activity
SH3 Domain Binding
Enzyme Binding
Protein Kinase Binding
Histone Deacetylase Binding
Biological Process
Apoptotic Process
Protein Ubiquitination
Regulation Of Ubiquitin-protein Transferase Activity
Branching Involved In Prostate Gland Morphogenesis
Epithelial Cell Maturation Involved In Prostate Gland Development
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of DNA Damage Checkpoint
DNA Replication Checkpoint
DNA Damage Checkpoint
DNA Catabolic Process, Exonucleolytic
DNA Replication
DNA Repair
Cellular Response To DNA Damage Stimulus
Intra-S DNA Damage Checkpoint
Cellular Response To Ionizing Radiation
Nucleic Acid Phosphodiester Bond Hydrolysis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
G2/M Checkpoints
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Major depressive disorder (
23377640
)
Protein-Protein Interactions
8 interactors:
APAF1
FAS
GLI1
HIF1AN
KIAA0319
NKX3-1
PPM1F
RAD9A
27 interactors:
ABL1
AR
ATAD5
ATM
BCL2
BCL2L1
CHEK2
CLSPN
COPS5
DNAJC7
FEM1B
HDAC1
HUS1
HUS1B
ITSN2
MLH1
MSH2
MSH3
MSH6
NR3C1
PCNA
RAD17
RAD9B
RPA1
RPA2
SF3B3
TOPBP1
Entrez ID
10116
5883
HPRD ID
16889
04788
Ensembl ID
ENSG00000172613
Uniprot IDs
Q9UK73
Q99638
PDB IDs
3A1J
3G65
3GGR
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of Peptidase Activity
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Proteolysis
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Regulation Of Endopeptidase Activity
Zymogen Activation
Cellular Response To Oxygen Levels
Regulation Of Peptidase Activity
Positive Regulation Of Signal Transduction
Regulation Of Proteolysis
Regulation Of Apoptotic Process
Protein Processing
Regulation Of Cell Death
Regulation Of Signal Transduction
Regulation Of Signaling
Cellular Response To Drug
Neuron Apoptotic Process
Apoptotic Signaling Pathway
Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Programmed Cell Death
Neuron Death
Positive Regulation Of Hydrolase Activity
Positive Regulation Of Response To DNA Damage Stimulus
Cell Death
Death
Response To Abiotic Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Tube Morphogenesis
Peptidyl-histidine Hydroxylation
Response To G1 DNA Damage Checkpoint Signaling
Peptidyl-asparagine Hydroxylation
Positive Regulation Of Protein Metabolic Process
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Positive Regulation Of Cellular Metabolic Process
Peptidyl-aspartic Acid Hydroxylation
Motor Neuron Apoptotic Process
Positive Regulation Of Androgen Secretion
Cellular Response To Stimulus
Regulation Of Response To DNA Damage Stimulus
Cellular Response To DNA Damage Stimulus
DNA Repair
Cellular Response To Stress
Mismatch Repair
Cell Cycle Process
DNA Metabolic Process
Cell Cycle
Cell Cycle Checkpoint
Negative Regulation Of Mitotic Cell Cycle
DNA Damage Checkpoint
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Cell Cycle
DNA Recombination
Response To Stress
Regulation Of Cell Cycle
Mitotic Cell Cycle Checkpoint
Negative Regulation Of DNA Metabolic Process
Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle
Cellular Aromatic Compound Metabolic Process
Intrinsic Apoptotic Signaling Pathway
Nucleobase-containing Compound Metabolic Process
Mitotic Cell Cycle Process
Response To Ionizing Radiation
Heterocycle Metabolic Process
Double-strand Break Repair
Cellular Nitrogen Compound Metabolic Process
Meiotic Mismatch Repair
Apoptotic Signaling Pathway
Nitrogen Compound Metabolic Process
Negative Regulation Of DNA Recombination
Regulation Of DNA Recombination
Cellular Response To Stimulus
B Cell Activation
Response To Radiation
DNA Replication
Positive Regulation Of Helicase Activity
Meiotic Nuclear Division
Somatic Recombination Of Immunoglobulin Gene Segments
Apoptotic Process
Somatic Diversification Of Immunoglobulins
Programmed Cell Death
Mitotic DNA Integrity Checkpoint
Cell Death
Meiotic Cell Cycle
Death
Meiosis I
Response To Abiotic Stimulus
B Cell Activation Involved In Immune Response
Somatic Hypermutation Of Immunoglobulin Genes
Tagcloud
?
11q13
250k
4ebp1
8p12
affymetrix
amplicon
amplicons
amplification
arrays
coamplification
coamplifications
coexpression
cores
eif4ebp1
enabled
encompassing
fgf19
fgf3
fgf4
fgfr1
gab2
gistic
nspi
oncogenes
pak1
ppapdc1b
rps6kb2
s6k2
synergy
Tagcloud (Difference)
?
11q13
250k
4ebp1
8p12
affymetrix
amplicon
amplicons
amplification
arrays
coamplification
coamplifications
coexpression
cores
eif4ebp1
enabled
encompassing
fgf19
fgf3
fgf4
fgfr1
gab2
gistic
nspi
oncogenes
pak1
ppapdc1b
rps6kb2
s6k2
synergy
Tagcloud (Intersection)
?