RAD9A and ATAD5

Number of citations of the paper that reports this interaction (PMID 15983387)
9

Data Source:
HPRD (in vitro)

		RAD9A	ATAD5
Gene Name		RAD9 homolog A (S. pombe)	ATPase family, AAA domain containing 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Checkpoint Clamp Complex	Nucleus
	Molecular Function	Protein Binding 3'-5' Exonuclease Activity Exodeoxyribonuclease III Activity SH3 Domain Binding Enzyme Binding Protein Kinase Binding Histone Deacetylase Binding	ATP Binding
	Biological Process	DNA Replication Checkpoint DNA Damage Checkpoint DNA Catabolic Process, Exonucleolytic DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Intra-S DNA Damage Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Cellular Response To DNA Damage Stimulus
Pathways		G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS			Height ( 23563607 18391951)
Protein-Protein Interactions		27 interactors: ABL1 AR ATAD5 ATM BCL2 BCL2L1 CHEK2 CLSPN COPS5 DNAJC7 FEM1B HDAC1 HUS1 HUS1B ITSN2 MLH1 MSH2 MSH3 MSH6 NR3C1 PCNA RAD17 RAD9B RPA1 RPA2 SF3B3 TOPBP1	2 interactors: PCNA RAD9A
Entrez ID		5883	79915
HPRD ID		04788	07792
Ensembl ID		ENSG00000172613	ENSG00000176208
Uniprot IDs		Q99638	Q96QE3
PDB IDs		3A1J 3G65 3GGR
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair Cellular Response To Stress Mismatch Repair Cell Cycle Process DNA Metabolic Process Cell Cycle Cell Cycle Checkpoint Negative Regulation Of Mitotic Cell Cycle DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cell Cycle DNA Recombination Response To Stress Regulation Of Cell Cycle Mitotic Cell Cycle Checkpoint Negative Regulation Of DNA Metabolic Process Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cellular Aromatic Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle Process Response To Ionizing Radiation Heterocycle Metabolic Process Double-strand Break Repair Cellular Nitrogen Compound Metabolic Process Meiotic Mismatch Repair Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Negative Regulation Of DNA Recombination Regulation Of DNA Recombination Cellular Response To Stimulus B Cell Activation Response To Radiation DNA Replication Positive Regulation Of Helicase Activity Meiotic Nuclear Division Somatic Recombination Of Immunoglobulin Gene Segments Apoptotic Process Somatic Diversification Of Immunoglobulins Programmed Cell Death Mitotic DNA Integrity Checkpoint Cell Death Meiotic Cell Cycle Death Meiosis I Response To Abiotic Stimulus B Cell Activation Involved In Immune Response Somatic Hypermutation Of Immunoglobulin Genes	Positive Regulation Of Deoxyribonuclease Activity DNA Replication Leading Strand Elongation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage DNA Repair Mitotic Cell Cycle Process Intra-S DNA Damage Checkpoint DNA Replication Checkpoint Translesion Synthesis Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Postreplication Repair Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Nuclear DNA Replication Telomere Maintenance Via Recombination Cell Cycle Process DNA Metabolic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening DNA Catabolic Process, Exonucleolytic Cell Cycle Transcription-coupled Nucleotide-excision Repair Cellular Response To Stress Positive Regulation Of Nuclease Activity Response To Cadmium Ion Cellular Response To Ionizing Radiation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Mismatch Repair Base-excision Repair Positive Regulation Of Response To DNA Damage Stimulus Telomere Maintenance Nucleotide-excision Repair Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint DNA-dependent DNA Replication DNA Biosynthetic Process Regulation Of DNA Replication Regulation Of Response To DNA Damage Stimulus Cellular Response To Radiation DNA Catabolic Process Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process DNA Damage Checkpoint Regulation Of Intrinsic Apoptotic Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint
Tagcloud ?		11q13 250k 4ebp1 8p12 affymetrix amplicon amplicons amplification arrays coamplification coamplifications coexpression cores eif4ebp1 enabled encompassing fgf19 fgf3 fgf4 fgfr1 gab2 gistic nspi oncogenes pak1 ppapdc1b rps6kb2 s6k2 synergy	ab abs accumulated breaks deaminase division eta haploinsufficiency haploinsufficient heterozygous hypermutation igg1 igh immunized instability interchromosomal isotypes joining proliferating prone recombination slowed splenic strand switch translocations unaffected unloading usage
Tagcloud (Difference) ?		11q13 250k 4ebp1 8p12 affymetrix amplicon amplicons amplification arrays coamplification coamplifications coexpression cores eif4ebp1 enabled encompassing fgf19 fgf3 fgf4 fgfr1 gab2 gistic nspi oncogenes pak1 ppapdc1b rps6kb2 s6k2 synergy	ab abs accumulated breaks deaminase division eta haploinsufficiency haploinsufficient heterozygous hypermutation igg1 igh immunized instability interchromosomal isotypes joining proliferating prone recombination slowed splenic strand switch translocations unaffected unloading usage
Tagcloud (Intersection) ?